• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Tobramycin, Free Base

Tobramycin, Free Base

Product ID T5604
Cas No. 32986-56-4
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $68.90 In stock
100 mg $104.00 In stock
500 mg $318.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective in the treatment of Pseudomonas infections. In vitro, tobramycin inhibits T cell and neutrophil migration. In separate cellular models, this compound also decreases activation of NF-κB, expression of MUC5AC, and phosphorylation of ERK and p38 MAPK.

Product Info

Cas No.

32986-56-4

Purity

≥98%

Formula

C18H37N5O9

Formula Wt.

467.51

Chemical Name

O-3-Amino-3-deoxy-α-d-glucopyranosyl-(1->6)-O- [2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl- (1->4)]-2-deoxy-D-streptamine

IUPAC Name

(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S, 6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl] oxy-6-(hydroxymethyl)oxane-3,5-diol

Synonym

Nebramycin factor 6, NF 6, Tobracin, Tobralex, Tobramaxin, Tobrex

Melting Point

178°C

Solubility

Soluble in water. Slightly soluble in ethanol. Practically insoluble in ether or chloroform.

Appearance

White to off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T5604 MSDS PDF

Info Sheet

T5604 Info Sheet PDF

References

Papich MG. Antibiotic treatment of resistant infections in small animals. Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1091-107. PMID: 23890241.

Gziut M, MacGregor HJ, Nevell TG, et al. Anti-inflammatory effects of tobramycin and a copper-tobramycin complex with superoxide dismutase-like activity. Br J Pharmacol. 2013 Mar;168(5):1165-81. PMID: 23072509.

Nakamura S, Yanagihara K, Araki N, et al. High-dose tobramycin inhibits lipopolysaccharide-induced MUC5AC production in human lung epithelial cells. Eur J Pharmacol. 2011 Mar 21. [Epub ahead of print]. PMID: 21414310.

Periti P. Tobramycin--clinical pharmacology and chemotherapy. J Chemother. 1996 Jan;8 Suppl 1:3-30. PMID: 8948764.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I0482

    S-(+)-Ibuprofen

    Optically active isomer of ibuprofen, NSAID; CO...

    ≥98%
  • P2817

    Phentolamine Hydrochloride

    ATP-sensitive K+ channel activator, α-adrenerg...

    ≥98%
  • R5722

    Rofecoxib

    NSAID; COX-2 inhibitor.

    ≥98%
  • N7200

    NS-11394

    GABA-A α5/3/2 positive modulator.

    ≥98%
  • M403007

    MK-3697

    Orexin 2 receptor antagonist

    ≥98%
  • S0072

    5S rRNA modificator

    Electrophile used in 2’-hydroxyl acylation of...

    ≥98%
  • V3378

    Vitamin B12

    Coenzyme, vitamin found in dairy, meat, eggs, f...

    ≥97%
  • V3345

    Vildagliptin

    DPP4 inhibitor.

    ≥98%
  • I7155

    Isoindigo

    Potential AhR binding agent.

    ≥98%
  • S5722

    Sofosbuvir

    Viral RNA polymerase inhibitor.

    ≥98%
  • A7202

    AS-604850

    p110γ PI3K inhibitor.

    ≥98%
  • T1004

    Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity

    Synthesis impurity

    ≥92%
  • P3465

    Piperine

    Alkaloid found in black and long peppers; TRPV1...

    ≥95%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • T7037

    Triptorelin Acetate

    Peptide, GnRH analog.

    ≥95%
  • G4482

    Glucagon-like Peptide I (7-37)

    Endogenous peptide hormone, GLP-1 fragment, inv...

    ≥95%
  • C3246

    Cilostazol

    Quinoline; PDE 3B inhibitor.

    ≥98%
  • U682042

    URB602

    Inhibitor of Monoacyglycerol lipase (MAGL).

    ≥98%
  • R2512

    RGD

    Tripeptide, binds cell surface integrins.

    ≥95%
  • D336486

    Dimethylamino Parthenolide

    Water-soluble parthenolide analog; NF-κB inhib...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only