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Triamcinolone Acetonide Acetate

Triamcinolone Acetonide Acetate

Product ID T7044
Cas No. 3870-07-3
Purity ≥97%
Product Unit SizeCostQuantityStock
50 mg $45.50 In stock
250 mg $121.80 In stock
1 g $330.00 In stock
5 g $918.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Triamcinolone is a glucocorticoid/steroid that downregulates expression of VEGF and exhibits anti-inflammatory and anti-angiogenic activities. Triamcinolone is clinically used to treat retinal edema and other ocular pathologies and may cause ocular hypertension.

Product Info

Cas No.

3870-07-3

Purity

≥97%

Formula

C26H33FO7

Formula Wt.

476.53

Chemical Name

(11β,16α)-9-Fluoro-11,12-dihydroxy-16,17-[1- methylethylidenebis-(oxy)]pregna-1,4-diene-3,20-dione 21-acetate.

IUPAC Name

[2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate

Synonym

Triamcinolone acetonide 21-acetate

Melting Point

268-270°C

Solubility

Sparingly soluble in ethanol, acetone.

Appearance

White or Almost White Crytalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T7044 MSDS PDF

Info Sheet

T7044 Info Sheet PDF

References

Zhou H, Yang L, Li H, et al. Downregulation of VEGF mRNA expression by triamcinolone acetonide acetate-loaded chitosan derivative nanoparticles in human retinal pigment epithelial cells. Int J Nanomedicine. 2012;7:4649-60. PMID: 22942646.

McAllister IL, Vijayasekaran S, Chen SD, et al. Effect of triamcinolone acetonide on vascular endothelial growth factor and occludin levels in branch retinal vein occlusion. Am J Ophthalmol. 2009 May;147(5):838-46, 846.e1-2. PMID: 19211093.

Mizuno D, Matsubara A, Ogura Y. Effect of posterior sub-tenon administration of triamcinolone acetonide on leukocyte dynamics in rat retinal microcirculation after panretinal photocoagulation. Invest Ophthalmol Vis Sci. 2008 May;49(5):2127-33. PMID: 18436845.

Custom Order

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