• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Tubeimoside I

Tubeimoside I

Product ID T8004
Cas No. 102040-03-9
Purity ≥96%
Product Unit SizeCostQuantityStock
10 mg $114.70 In stock
25 mg $229.30 In stock
100 mg $744.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tubeimoside I is a triterpene saponin originally found in Bolbostemma that exhibits anti-inflammatory, antiviral, anticancer chemotherapeutic, and chemopreventive activities. Tubeimoside I inhibits LPS-stimulated production of TNF-α, IL-1β, and IL-6, preventing the development of pulmonary edema and infiltration of inflammatory cells in vivo. Tubeimoside I also induces G2/M phase cell cycle arrest and mitochondria-dependent apoptosis in esophageal squamous cell carcinoma cells, inhibiting cell proliferation; in other, similar cellular and animal models, this compound inhibits cell and tumor growth. Tubeimoside I binds tubulin at the colchicine site, inhibiting microtubule polymerization. Additionally, this compound inhibits production of HIV core protein p24 and infectivity of HIV-1 in vitro.

Product Info

Cas No.

102040-03-9

Purity

≥96%

Formula

C63H98O29

Formula Wt.

1319.43

Synonym

Tubeimoside 1

Melting Point

250-252°C

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T8004 MSDS PDF

Info Sheet

T8004 Info Sheet PDF

References

Wu Q, Sun G, Yuan X, et al. Tubeimoside-1 attenuates LPS-induced inflammation in RAW 264.7 macrophages and mouse models. Immunopharmacol Immunotoxicol. 2013 Aug;35(4):514-23. PMID: 23844578.

Xu Y, Wang G, Chen Q, et al. Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death. Chin J Cancer Res. 2013 Jun;25(3):312-21. PMID: 23825908.

Ma R, Song G, You W, et al. Anti-microtubule activity of tubeimoside I and its colchicine binding site of tubulin. Cancer Chemother Pharmacol. 2008 Sep;62(4):559-68. PMID: 18030471.

Yu L, Ma R, Wang Y, et al. Potent anti-tumor activity and low toxicity of tubeimoside 1 isolated from Bolbostemma paniculatum. Planta Med. 1994 Jun;60(3):204-8. PMID: 8073083.

Yu LJ, Ma RD, Jiang SB. Effects of tubeimoside-1 on HIV core protein p24 and cytopathogenesis in vitro. Zhongguo Yao Li Xue Bao. 1994 Mar;15(2):103-6. PMID: 8010099.

Yu LJ, Ma RD, Wang YQ, et al. Potent anti-tumorigenic effect of tubeimoside 1 isolated from the bulb of Bolbostemma paniculatum (Maxim) Franquet. Int J Cancer. 1992 Feb 20;50(4):635-8. PMID: 1537629.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F4682

    Fluconazole

    Triazole; 14-α demethylase inhibitor.

    ≥98%
  • P2816

    S-(N-3-Phenylpropylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate.

    ≥98%
  • C0375

    Ac-DEVD-pNA

    Caspase 3 substrate.

    ≥95%
  • C1868

    Cerebellin

    Peptide, involved in synapse formation and cell...

    ≥95%
  • A6002

    Apamin

    Peptide, bee venom toxin; SK2/3/4 K+ channel bl...

    ≥95%
  • Z161022

    α-Zearalanol

    Mycotoxin that has structural similarity to est...

    ≥98%
  • G0244

    alpha-Galactosylceramide

    Synthetic glycolipid found in Agelas mauritaniu...

    ≥96%
  • P3563

    Piperlonguminine

    Found in Piper longum.

    ≥99%
  • C0824

    CCG1423

    Serum response factor inhibitor and MRTF-A bind...

    ≥98%
  • A0962

    Adrenocorticotropic Hormone (1-4)

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • T1968

    Terpinen-4-ol

    Monoterpene found in various plant sources.

    ≥98%
  • F4482

    Fluvastatin Sodium

    Statin; HMG-CoA reductase inhibitor, potential ...

    ≥98%
  • F4683

    Fluticasone Propionate

    β2-adrenergic agonist.

    ≥98%
  • P7060

    Protocatechuic Acid Ethyl Ester

    Dihydroxyphenolic acid found in cruciferous veg...

    ≥98%
  • B3373

    Bis(aziridinyl)methylamino Phosphine Sulfide

    Insect sterilizer; mutagenic.

    ≥98%
  • P1969

    Perifosine

    Alkylphospholipid analog; Akt inhibitor.

    ≥98%
  • B8144

    Bulleyaconitine A

    Found in Aconitum bulleyanum; voltage-gated Na+...

    ≥95%
  • B6807

    [Des-Arg9]-Bradykinin

    Natriuretic, vasodilatory peptide, bradykinin a...

    ≥95%
  • V3253

    Vinblastine Sulfate

    Vinca alkaloid found in Catharanthus; microtubu...

    ≥96%
  • V3355

    Vindoline

    Semi-synthetic vinca alkaloid found in Catharan...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only