• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Urotensin II, human

Urotensin II, human

Product ID U6959
Cas No. 251293-28-4
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $194.30 Please Inquire
1 mg $341.30 Please Inquire
2.5 mg $630.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Urotensin II is a peptide ligand that binds the urotensin II (UT) receptor and can be used as a biomarker for hypertension and type 2 diabetes. Urotensin II increases expression of IL-6, IL-1β, VCAM-1, and tissue factor in vitro, exhibiting pro-inflammatory activity. Urotensin II also inhibits glucose transport through modulation of NADPH oxidase signaling, which increases levels of ROS and decreases phosphorylation of Akt, ERK1/2, and p38 MAPK. Additionally, urotensin II can induce apoptosis in cardiac tissue cells and can induce relaxation in smooth muscle cells.

Product Info

Cas No.

251293-28-4

Purity

≥95%

Formula

C64H85N13O18S2

Formula Wt.

1388.6

Solubility

Soluble in water (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

U6959 MSDS PDF

Info Sheet

U6959 Info Sheet PDF

References

Peng H, Zhang M, Cai X, et al. Association between Human Urotensin II and Essential Hypertension-A 1:1 Matched Case-Control Study. PLoS One. 2013 Dec 10;8(12):e81764. PMID: 24339964.

Wang HX, Wu XR, Yang H, et al. Urotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway. PLoS One. 2013 Oct 8;8(10):e76796. PMID: 24116164.

Park SL, Lee BK, Kim YA, et al. Inhibitory Effect of an Urotensin II Receptor Antagonist on Proinflammatory Activation Induced by Urotensin II in Human Vascular Endothelial Cells. Biomol Ther (Seoul). 2013 Jul 30;21(4):277-83. PMID: 24244812.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C2942

    Mechlorethamine Hydrochloride

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • K0144

    Kallikrein Inhibitor

    Peptide; serine protease inhibitor.

    ≥95%
  • B5609

    Boc-GRR-AMC

    Peptide, protease substrate.

    ≥98%
  • B5072

    BMS-754807

    InsR and IGF-1R inhibitor.

    ≥99%
  • K0088

    Kawain

    Kavalactone originally found in Piper methystic...

    ≥98%
  • T6902

    Tranilast

    Mast cell stabilizer; TRPV2 antagonist, PDGFR i...

    ≥98%
  • P9768

    Pyronaridine Tetraphosphate

    Hemantin inhibitor.

    ≥98%
  • I0516

    I-BET151

    BRD2/3/4 inhibitor.

    ≥98%
  • O9302

    Oxacillin Sodium Monohydrate

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • G8225

    Guggulsterone

    Steroid found in myrrh; FXR antagonist.

    ≥98%
  • P7359

    Psoralidin

    Phenol found in Psoralea coryfolia.

    ≥98%
  • E2002

    Efaroxan Hydrochloride

    α2-adrenergic and imidazoline-1 antagonist, AT...

    ≥99%
  • H1672

    Hesperetin

    Flavanone found in species of Citrus; L-type Ca...

    ≥97%
  • B3573

    Bisdemethoxycurcumin

    Curcumin derivative; DNMT1 and α-amylase inhib...

    ≥98%
  • P3597

    Pizotyline Malate

    5-HT1A partial agonist, 5-HT2C antagonist.

    ≥98%
  • H1794

    Hexamethonium Bromide Hydrate

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • T3132

    Thiazovivin

    ROCK inhibitor.

    ≥98%
  • A5326

    Aniracetam

    AMPA positive allosteric modulator, D2, 5-HT2A,...

    ≥98%
  • E0929

    Echinacoside

    Phenylethanoid glycoside found in Echinacea.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only