Description
Vitamin E acetate is a derivative of vitamin E that exhibits neuroprotective, antioxidative, and anticancer chemopreventive activities. In animal models of sciatic nerve crush injury, vitamin E acetate improves motor nerve conduction velocity and suppresses the progression of thermal hyperalgesia. In other animal models, this compound inhibits vanadium-induced adrenocortical hypertrophy as well as perturbations in testicular lipid peroxidation and antioxidative enzyme activity. In animal models exposed to UV light, vitamin E acetate delays tumor formation and tumor yield, preventing skin carcinogenesis.