Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Product Unit Size | Cost | Quantity | Stock |
|---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Cas No. | 1246560-33-7 |
|---|---|
| Purity | ≥98% |
| Formula | C17H22N8O |
| Formula Wt. | 354.41 |
| IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
| Synonym | SB2343, SB-2343, VS5584 |
| Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
Statin; HMG-CoA reductase inhibitor, potential ...
Mixture of pyrantel, a thiophene, and pamoic ac...
SIRT inhibitor.
MET inhibitor.
Endogenous sphingolipid involved in cell signal...
Organosulfur found in garlic; kinesin Eg5 inhib...
Vinca alkaloid found in Catharanthus; microtubu...
SARS-CoV-2 inhibitor
Type A trichothecene mycotoxin produced by Fusa...
Indole found in cruciferous vegetables; AhR ago...
Thalidomide derivative; cereblon and TNF-α inh...
Tetracycline; protein translation inhibitor, po...
Peptide, alters uterine contractility; V1/2 and...
Dihydropyrazine found in Ligusticum walliichi. ...
Thienylbutyl ITC analog.
Mycotoxin produced by Fusarium fungi that infec...
Anxiolytic-like agent that stimulates angiogene...
Anthracycline, DNA intercalator; topoisomerase ...
Lincosamide; peptidyl transferase inhibitor, pr...
Trichothecene mycotoxin produced by Fusarium.