Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Product Unit Size | Cost | Quantity | Stock |
|---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Cas No. | 1246560-33-7 |
|---|---|
| Purity | ≥98% |
| Formula | C17H22N8O |
| Formula Wt. | 354.41 |
| IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
| Synonym | SB2343, SB-2343, VS5584 |
| Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
Peptide; FRP1 antagonist.
Synthetic steroid hormone; ER antagonist.
Endogenous peptide, involved in paracrine and a...
Enalapril analog; ACE inhibitor.
Selective inhibitor of the γ isoform of PI3K (...
TTK/CLK2 inhibitor.
Semi-synthetic diterpene originally found in Ta...
Naturally produced ITC, sulfonyl analog of sulf...
Tyrosine kinase inhibitor.
Coccidiostat; dihydrofolate reductase inhibitor...
PI3K and mTOR inhibitor.
Triterpene saponin found in species of Panax.
Endogenous opioid peptide; δOR and μOR agonis...
Macrolide antibiotic; vacuolar H+ ATPase inhibi...
EZH2 HMT inhibitor.
O-GlcNAcase inhibitor.
Corticosteroid
Fluoroquinolone; topoisomerase IV, topoisomeras...
AR antagonist.
Smac mimetic; IAP inhibitor.