Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Product Unit Size | Cost | Quantity | Stock |
---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Cas No. | 1246560-33-7 |
---|---|
Purity | ≥98% |
Formula | C17H22N8O |
Formula Wt. | 354.41 |
IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
Synonym | SB2343, SB-2343, VS5584 |
Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
β2-adrenergic agonist.
β1/2-adrenergic antagonist.
PARP inhibitor; potential Pim1 inhibitor.
Amino acid alcohol.
Macrolide lactone found in Bugula; TLR4 activat...
M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...
Cysteine-ITC conjugate, BITC derivative, antiox...
Proteasome inhibitor.
AhR antagonist.
Tyrphostin; IGF-1R inhibitor.
Hedgehog and Smo agonist.
EGFR inhibitor.
Non-depolarizing NMJ blocker; nAChR antagonist....
Nucleoside (deoxyguanosine) analog; DNA chain t...
Endogenous peptide hormone, involved in secreti...
Aminoquinoline, binds heme, causes cell lysis.<...
PI3K and HDAC inhibitor.
Amino acid precursor of dopamine.
Synthesis intermediate
Nonpeptide angiotensin II receptor antagonist