Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Product Unit Size | Cost | Quantity | Stock |
|---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
| Cas No. | 1246560-33-7 |
|---|---|
| Purity | ≥98% |
| Formula | C17H22N8O |
| Formula Wt. | 354.41 |
| IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
| Synonym | SB2343, SB-2343, VS5584 |
| Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
Synthetic hydrocortisone derivative; glucocorti...
Synthetic compound related to sulforaphane.
MET, VEGFR2, Ron, Axl, FLT3 inhibitor.
ITC found in cruciferous vegetables, analog of ...
B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit...
Labdane diterpene found in Coleus; PP2A and ade...
Endogenous thyroid hormone T4.
Histamine H1 antagonist, FIASMA.
Ellagic acid derivative produced by gut microfl...
β-lactam; penicillin binding protein inhibitor...
Nitrogen mustard, DNA alkylator.
β2-adrenergic agonist.
Endogenous peptide hormone, GLP-1 fragment, inv...
Inhibitor of EGFR.
Shellfish toxin produced by dinoflagellates and...
Alliin analog found in cruciferous vegetables.<...
Roscovitine analog; CDK inhibitor.
Nucleoside (guanosine) analog; DNA chain termin...
Sesquiterpene alkaloid found in Huperzia serrat...