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Ziconotide

Ziconotide

Product ID Z324098
Cas No. 107452-89-1
Purity ≥95%
Product Unit SizeCostQuantityStock
100 µg $157.50 In stock
0.5 mg $498.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
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  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Ziconotide in an ω-conopeptide originally isolated from the venom of a marine snail. Ziconotide has been shown to prevent neuronal damage resulting from cerebral ischemia in Fischer-344 rats. Furthermore, ziconotide is a selective N-type calcium channel blocker, non-opioid analgesic.

Product Info

Cas No.

107452-89-1

Purity

≥95%

Formula

C102H172N36O32S7

Formula Wt.

2639.16

Synonym

ω-Conotoxin MVIIA, SNX-111

Solubility

Soluble in 1% acetic acid (1 mg/mL), water, PBS.

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

Z324098 MSDS PDF

Info Sheet

Z324098 Info Sheet PDF

References

Valentino K, Newcomb R, Badbois T, et al. A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. Proc Natl Acad Sci USA. 1993 Aug 15;90(16):7894-7897. PMID: 8102803.

Pringle AK, Benham CD, Sim L, et al. Selective N-type calcium channel antagonist omega conotoxin MVIIA is neuroprotective against hypoxic neurodegeneration in organotypic hippocampal-slice cultures. Stroke. 1996 Nov;27(11):2124-2130. PMID: 8898826.

Berman RF, Verweij BH, Muizelaar JP. Neurobehavioral protection by the neuronal calcium channel blocker ziconotide in a model of traumatic diffuse brain injury in rats. J Neurosurg. 2000 Nov;93(5):821-828. PMID: 11059664.

Pope JE, Deer TR, Bruel BM, et al. Clinical uses of intrathecal therapy and its placement in the pain care algorithm. Pain Pract. 2016 Feb 23. doi:10.1111/papr.12438. PMID: 26914961.

Custom Order

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