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(−)-Gallocatechin

(−)-Gallocatechin

Product ID G0243
Cas No. 3371-27-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $125.80 In stock
10 mg $226.50 In stock
25 mg $490.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

(-)-Gallocatechin is a polyphenol originally derived from a variety of sources, including green tea, coffee, safflower, and almonds; it is the epimer of (-)-epigallocatechin. (-)-Gallocatechin, like other catechins, exhibits a variety of beneficial properties, including anti-diabetic, antioxidative, antiviral, and antibacterial activities. In vivo, (-)-gallocatechin inhibits α-amylase, decreasing absorption of carbohydrates and preventing increases in blood glucose levels. This compound increases radical scavenging in vitro and also inhibits the hemorrhagic activities of matrix metalloproteinases. In vitro, (-)-gallocatechin directly inhibits HIV-1 reverse transcriptase and integrase, also upregulating expression of IL-2 and downregulating expression of IL-10 and TNF-α. (-)-Gallocatechin decreases osteoclastogenesis, inhibits osteoclast differentiation and resulting in a positive effect on bone metabolism. This compound also inhibits gram positive bacteria, preventing formation of Streptococcus-induced dental caries.

Product Info

Cas No.

3371-27-5

Purity

≥98%

Formula

C15H14O7

Formula Wt.

306.27

Chemical Name

(2S,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

IUPAC Name

(2S,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

Melting Point

200°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

G0243 MSDS PDF

Info Sheet

G0243 Info Sheet PDF

Brochures

Green Tea Flyer

Natural Products Flyer

Antivirals Booklet

References

Tsujita T, Shintani T, Sato H. α-Amylase inhibitory activity from nut seed skin polyphenols. 1. Purification and characterization of almond seed skin polyphenols. J Agric Food Chem. 2013 May 15;61(19):4570-6. PMID: 23614772.

Colon M, Nerin C. Role of catechins in the antioxidant capacity of an active film containing green tea, green coffee, and grapefruit extracts. J Agric Food Chem. 2012 Oct 3;60(39):9842-9. PMID: 22973940.

F Vale LH, Mendes MM, Fernandes RS, et al. Protective effect of schizolobium parahyba flavonoids against snake venoms and isolated toxins. Curr Top Med Chem. 2011;11(20):2566-77. PMID: 21682680

Jiang Y, Ng TB, Liu Z, et al. Immunoregulatory and anti-HIV-1 enzyme activities of antioxidant components from lotus (Nelumbo nucifera Gaertn) rhizome. Biosci Rep. 2010 Nov 30. PMID: 21114474.

Ko CH, Lau KM, Choy WY, et al. Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism. J Agric Food Chem. 2009 Aug 26;57(16):7293-7. PMID: 19653629.

Ferrazzano GF, Amato I, Ingenito A, et al. Anti-cariogenic effects of polyphenols from plant stimulant beverages (cocoa, coffee, tea). Fitoterapia. 2009 Jul;80(5):255-62. PMID: 19397954.

Custom Order

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