Hydrocortisone 21-Acetate

Name: Hydrocortisone 21-Acetate
SKU: H9612
Availability: InStock

Product ID H9612

Cas No. 50-03-3

Purity ≥98%

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Description

Hydrocortisone is a steroid hormone that is produced in the adrenal cortex and is involved in stress signaling. Hydrocortisone is a glucocorticoid and is also known as cortisol in its endogenous form; it exhibits anti-inflammatory and immunomodulatory activities. Hydrocortisone is clinically used to treat eczema, psoriasis, gout, and severe allergic reactions. Hydrocortisone stimulates gluconeogenesis, inhibits inflammatory cytokine production, and shifts the immune response from Th1 to Th2 subtype.

Product Info

Cas No.	50-03-3
Purity	≥98%
Formula	C₂₃H₃₂O₆
Formula Wt.	404.50
Chemical Name	(11β)11,17,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
IUPAC Name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2, 6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Synonym	Colifoam, Cortaid, Cortifoam, Hydrocal, Lanacort, Sigmacort, Velopural
Melting Point	223°C(dec)
Solubility	Soluble in DMF and dioxane. Slightly soluble in chloroform, ethanol (4 mg/mL), methanol. ether and water.
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	H9612 MSDS PDF
Info Sheet	H9612 Info Sheet PDF

References

Angelier F, Wingfield JC. Importance of the glucocorticoid stress response in a changing world: theory, hypotheses and perspectives. Gen Comp Endocrinol. 2013 Sep 1;190:118-28. PMID: 23770214.

Tarchalska-Kryńska B. Glucocorticosteroids: mechanism of action, pharmacological effects, pharmacokinetics and adverse effects. Otolaryngol Pol. 1994;48 Suppl 17:41-8. PMID: 8090502.

Sluyser M. Mechanism of steroid hormone action at the cellular level. Basic Life Sci. 1975;6:79-104. PMID:168860.

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Hydrocortisone 21-Acetate

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Description

Product Info

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Downloads

References

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