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Cetrimide

Cetrimide

Product ID C1878
Cas No. 57-09-0
Purity ≥98%
Product Unit SizeCostQuantityStock
50 g $44.10 In stock
250 g $99.20 In stock
500 g $159.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cetrimide is a mix of quaternary ammonium salts that exhibits antiseptic and anticancer chemotherapeutic activities. Cetrimide acts as a cationic detergent, altering the mitochondrial membrane potential and inducing pore formation in membranes. Cetrimide bromide inhibits H+ ATP synthase, inducing mitochondrial membrane depolarization and caspase activation and inhibiting proliferation in cellular and animal models of head and neck cancers.

Product Info

Cas No.

57-09-0

Purity

≥98%

Formula

C19H42BrN

Formula Wt.

364.45

Chemical Name

N,N,N-Trimethyl-1-hexadecanaminium bromide

IUPAC Name

hexadecyl(trimethyl)azanium;bromide

Synonym

Cetrimonium Bromide, Bromat, Cetab, Lissolamine V, Micol, Quamonium, Hexadecyltrimethylammonium bromide

Melting Point

248-251°C

Solubility

Soluble in 1 M water at 20oC. Sparingly soluble in acetone.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C1878 MSDS PDF

Info Sheet

C1878 Info Sheet PDF

References

Ito E, Yip KW, Katz D, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol. 2009 Nov;76(5):969-83. PMID: 19654225.

Bragadin M, Dell'Antone P. Mitochondrial bioenergetics as affected by cationic detergents. Arch Environ Contam Toxicol. 1996 Feb;30(2):280-4. PMID: 8593085.

Custom Order

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