• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dasatinib

Dasatinib

Product ID D023721
Cas No. 302962-49-8
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $48.00 In stock
100 mg $89.00 In stock
250 mg $239.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dasatinib is an anticancer chemotherapeutic compound that inhibits Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Dasatinib is clinically used to treat chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL); in acute myelogenous leukemia (AML) cells, dasatinib induces myeloid differentiation and autophagy. Dasatinib also displays antiviral activity, preventing dengue virus infection through its inhibition of FYN kinase.

Product Info

Cas No.

302962-49-8

Purity

≥99%

Formula

C22H26ClN7O2S

Formula Wt.

488.01

IUPAC Name

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide

Synonym

BMS354825, BMS-354825, Sprycel

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D023721 MSDS PDF

Info Sheet

D023721 Info Sheet PDF

References

Xie N, Zhong L, Liu L, et al. Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells. Biochem Pharmacol. 2014 May 1;89(1):74-85. PMID: 24607273.

de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol. 2013 Jul;87(13):7367-81. PMID: 23616652.

Montero JC, Seoane S, Ocaña A, et al. Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. Clin Cancer Res. 2011 Sep 1;17(17):5546-52. PMID: 21670084.

Das J, Chen P, Norris D, et al. 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem. 2006 Nov 16;49(23):6819-32. PMID: 17154512.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S0133

    Saikosaponin C

    Triterpene saponin found in Bupleurum.

    ≥98%
  • O6805

    Orbifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥99%
  • A9715

    AZD-8330

    MEK 1/2 inhibitor.

    ≥98%
  • S800000

    SU-9516

    CDK2 inhibitor.

    ≥98%
  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • D4802

    17-Dimethylaminoethylamino Demethoxygeldanamycin

    Geldanamycin derivative; HSP90 inhibitor.

    ≥98%
  • G1308

    GDC-0032

    PI3K inhibitor.

    ≥98%
  • G0181

    Gastrin Releasing Peptide, human

    Endogenous bombesin-like peptide, involved in f...

    ≥95%
  • A5132

    Amikacin Disulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • C0263

    L-Carnitine Hydrochloride

    Endogenous quaternary ammonium, required for fa...

    ≥98%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • A5072

    Amsacrine

    Acridine derivative, DNA intercalator; topoisom...

    ≥98%
  • I6068

    Ipriflavone

    Synthetic isoflavone.

    ≥98%
  • C9609

    Cyclophosphamide Monohydrate

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • N1989

    Neurotensin

    Endogenous neuropeptide involved in hormone rel...

    ≥95%
  • G0096

    GAY

    Tripeptide, used to tag proteins.

    ≥95%
  • N0262

    Naphazoline Hydrochloride

    α1-adrenergic agonist.

    ≥97%
  • F334451

    Filipin Complex

    A probe for cholesterol in biological membranes...

    ≥97%
  • G7345

    GSK-2606414

    PERK inhibitor.

    ≥99%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2026 LKT Laboratories, All Rights Reserved - Products for research use only