• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dasatinib

Dasatinib

Product ID D023721
Cas No. 302962-49-8
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $48.00 In stock
100 mg $89.00 In stock
250 mg $239.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dasatinib is an anticancer chemotherapeutic compound that inhibits Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Dasatinib is clinically used to treat chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL); in acute myelogenous leukemia (AML) cells, dasatinib induces myeloid differentiation and autophagy. Dasatinib also displays antiviral activity, preventing dengue virus infection through its inhibition of FYN kinase.

Product Info

Cas No.

302962-49-8

Purity

≥99%

Formula

C22H26ClN7O2S

Formula Wt.

488.01

IUPAC Name

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide

Synonym

BMS354825, BMS-354825, Sprycel

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D023721 MSDS PDF

Info Sheet

D023721 Info Sheet PDF

References

Xie N, Zhong L, Liu L, et al. Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells. Biochem Pharmacol. 2014 May 1;89(1):74-85. PMID: 24607273.

de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol. 2013 Jul;87(13):7367-81. PMID: 23616652.

Montero JC, Seoane S, Ocaña A, et al. Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. Clin Cancer Res. 2011 Sep 1;17(17):5546-52. PMID: 21670084.

Das J, Chen P, Norris D, et al. 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem. 2006 Nov 16;49(23):6819-32. PMID: 17154512.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • Y1000

    Y27632 Dihydrochloride

    ROCK inhibitor.

    ≥99%
  • T1776

    D-Tetrahydropalmatine

    Alkaloid found in Corydalis; D1 antagonist, org...

    ≥99%
  • D5690

    Doxazosin Mesylate

    Quinazoline; α1-adrenergic antagonist.

    ≥98%
  • A0902

    N-Acetyl-S-(N′-phenylhexylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant; HDAC inhib...

    ≥98%
  • A4849

    Amyloid-β (25-35)

    Endogenous APP peptide cleavage product, primar...

    ≥95%
  • G823720

    Gusacitinib

    SYK/JAK inhibitor

    ≥98%
  • Z1602

    Zearalenone

    Mycotoxin produced by Fusarium; ER agonist.

    ≥98%
  • M1746

    Melphalan

    Nitrogen mustard, DNA alkylator.

    ≥95%
  • A9712

    AZD-6482

    p110β PI3K inhibitor.

    ≥98%
  • A600002

    AP-26113

    Pan inhibitor of ALK.

    ≥98%
  • P2002

    PF-04691502 Dihydrate

    PI3K and mTOR inhibitor.

    ≥98%
  • D0263

    Dapoxetine Hydrochloride

    SERT inhibitor, potential voltage-gated K+ chan...

    ≥99%
  • P9671

    Pyrazinamide

    Nicotinamide analog prodrug; fatty acid synthet...

    ≥98%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • S7871

    Stresscopin, human

    Peptide, urocortin III analog; CRFR2 agonist.

    ≥95%
  • G8800

    GW-788388

    ALK5 (activin-like) antagonist.

    ≥97%
  • T5611

    δ-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • M0273

    Mastoparan 8

    Antimicrobial peptide found in bee and wasp ven...

    ≥95%
  • L9704

    LY-2603618

    Chk1 inhibitor.

    ≥98%
  • M1677

    11-Methoxyyangonin

    Minor kavalactone originally found in Piper met...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2026 LKT Laboratories, All Rights Reserved - Products for research use only