Description
This peptide is a substrate for caspase 3 and is used to measure caspase 3 activation.
This peptide is a substrate for caspase 3 and is used to measure caspase 3 activation.
| Purity | ≥95% |
|---|---|
| Formula | C26H34N6O13 |
| Formula Wt. | 638.6 |
| Synonym | Caspase 3 substrate, colorimetric |
| Solubility | Slightly soluble in water. Soluble in DMSO, PBS. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Mahdavi M, Davoodi J, Zali MR, et al. Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomed Pharmacother. 2011 Jun;65(3):175-82. PMID: 21565459.
Kluza J, Lansiaux A, Wattez N, et al. Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Cancer Res. 2000 Aug 1;60(15):4077-84. PMID: 10945613
Flavonoid glycoside found in Scutellaria.
Allosteric inhibitor
Pan inhibitor of ALK.
ACE inhibitor.
ITC, erucin analog.
SIRT inhibitor.
Epoxide metabolite of acrylamide, induces DNA a...
Quaternary base alkaloid found in Phellodendron...
ROCK inhibitor.
Anti-metastatic
Oxazolidone derivative; Factor Xa inhibitor.
Nucleobase (adenine) analog; DNA polymerase inh...
Chalcone kavalactone found in Piper methysticum...
Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...
5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...
Mycotoxin produced by Aspergillus and Penicillu...
Selective HDAC4 and HDAC5 inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
NSAID; COX-1/2 inhibitor.
SERM.