LKT Labs

Biochemicals for Life Science Research

MLN-2238

MLN-2238

Product ID M4455
Cas No. 1072833-77-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $58.50 In stock
5 mg $194.70 In stock
10 mg $356.90 In stock
Bulk Quote

Quicklinks

Description

MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.

Product Info

Cas No.

1072833-77-2

Purity

≥95%
Formula

C14H19BCl2N2O4
Formula Wt.

361.03
IUPAC Name

[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
Synonym

Ixazomib
Solubility

DMSO 72 mg/mL (199.42 mM) Ethanol 9 mg/mL (24.92 mM) Water Insoluble
Appearance

White Powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

M4455 MSDS PDF
Info Sheet

M4455 Info Sheet PDF

References

Tian Z, Zhao JJ, Tai YT, et al. Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells. Blood. 2012 Nov 8;120(19):3958-67. PMID: 22983447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F5871

    N-formyl-Met-Leu-Phe-Lys

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • V0245

    Valdecoxib

    NSAID; CB1 agonist, COX-2 inhibitor.

    ≥98%
  • A1202

    Adapalene

    Tretinoin analog; RARα/β/γ agonist.

    ≥98%
  • A4443

    L-(+)-Alliin

    Optically active cysteine derivative found in A...

    ≥98%
  • T3031

    Thienylbutyl Isothiocyanate

    ITC.

    ≥96%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • R1776

    Resveratrol

    Phenolic phytoalexin found in soy, grapes, and ...

    ≥99%
  • T0091

    7-(Triethylsilyl)-10-deacetylbaccatin III

    Taxol derivative.

    ≥97%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • O610292

    Ophiobolin B

    Naturally occurring sesteterpenoid.

    ≥98%
  • K9200

    KX1-004

    Indole; Src inhibitor.

    ≥98%
  • K0038

    Kahweol Oleate

    Diterpene found in coffee beans.

    ≥98%
  • O6953

    Ornidazole

    5-Nitroimidazole derivative; genotoxic.

    ≥98%
  • O9497

    Oxytocin

    Endogenous neuropeptide hormone, involved in so...

    ≥95%
  • R183731

    Resiquimod

    Toll-like receptor 7/8 agonist

    ≥98%
  • U8000

    U-74389G

    Antioxidant shown to improve renal function.

    ≥95%
  • W9600

    WZ-4002

    EGFR (T790M) inhibitor.

    ≥98%
  • P2516

    S-(N-Phenylbutylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • M0125

    Magnolol

    Lignan found in Magnolia; GABA-A potentiator.

    ≥98%
  • B1876

    Betamethasone

    Steroid; glucocorticoid agonist.

    ≥98%