Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846
Product ID L2800
Cas No. 639052-78-1
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 639052-78-1 |
|---|---|
| Purity | ≥98% |
| Formula | C16H13ClN2OS |
| Formula Wt. | 316.80 |
| IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
| Solubility | 100mM in DMSO |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Schulte A, Kolarski D, Sundaram V, et al. Light-control over casein kinase 1delta activity with photopharmacology: a clear case for arylazopyrazole-based inhibitors. Int J Mol Sci. 2022 May 10;23(10):5326. PMID: 35628143.
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.