Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
Cas No. | 639052-78-1 |
---|---|
Purity | ≥98% |
Formula | C16H13ClN2OS |
Formula Wt. | 316.80 |
IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
Solubility | 100mM in DMSO |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
Abl, c-Kit, PDGFR inhibitor.
Metabolite of clofibrate; PPARα agonist.
Labdane diterpene found in Andrographis.
Natural antibiotic found in Streptomyces parvul...
Dual inhibitor of PI3K and mTOR.
Syk inhibitor.
Endogenous amino acid, also found in meat, dair...
Alkaloid found in species of Loranthus, Calia, ...
Carotenoid found in shrimp, salmon, and algae.<...
5-HT1A partial agonist, 5-HT2, histamine, α1/2...
PERK inhibitor.
Nitroimidazole; microtubule polymerization inhi...
Fibrate; PPARα agonist.
Nicotinamide analog prodrug; fatty acid synthet...
p110δ PI3K inhibitor.
Phallotoxin found in Amanita phalloides; microt...
Abl (T315I) inhibitor.
Fungal pigment found in red yeast rice
p38 MAPK inhibitor.
Histone H2-derived antimicrobial peptide found ...