Description
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
Cas No. | 639052-78-1 |
---|---|
Purity | ≥98% |
Formula | C16H13ClN2OS |
Formula Wt. | 316.80 |
IUPAC Name | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
Solubility | 100mM in DMSO |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
Prenylated phenolic terpene found in various pl...
Endogenous peptide hormone; CCK2 agonist, indir...
Steroidal saponin found in Dioscorea.
CDK4/6 inhibitor.
Macrolide; ET antagonist, proteasome inhibitor....
FGFR inhibitor.
Rapamycin impurity
RyR agonist, SIRT, telomerase, P2Y, GPCR inhibi...
Flavonoid found in Epimedium.
Protein translation inhibitor, peptidyl transfe...
T-type calcium channel blocker
Endogenous calcitonin-family peptide, involved ...
Found in Piper longum; TxA2 antagonist, ubiquit...
Aromatic retinoid; RAR, RXR agonist.
PDE and adenosine deaminase inhibitor.
Endogenous peptide hormone, involved in feeding...
FIASMA, 5-HT3 and σ1 agonist, SERT inhibitor.<...
Sulfonylurea; ATP-sensitive K+ channel blocker....
Endogenous RF-amide peptide, involved in nocice...
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...