Description
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
NG-52 is a purine and analog of purvalenol A that exhibits antimicrobial activity. NG-52 inhibits cyclin-dependent kinase 2 (CDK2), Cdc28p, and Pho85p. This compound also inhibits survival of Saccharomyces.
Cas No. | 212779-48-1 |
---|---|
Purity | ≥98% |
Formula | C16H19ClN6O |
Formula Wt. | 346.81 |
Chemical Name | 2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine |
IUPAC Name | 2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol |
Synonym | Compound 52 |
Solubility | 10 mM in DMSO, 50 mg/mL in methylene chloride: |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Gray NS, Wodicka L, Thunnissen AM, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. PMID: 9677190.
Alkaloid found in Sinomenium; acid-sensing ion ...
Smoothened agonist.
Antifungal antibiotic
Peptide fragment, renin substrate, precursor to...
p53 inhibitor
Potent and selective inhibitor
Lincosamide; ribosomal translocation and protei...
Taxane found in Taxus; potential microtubule de...
Trichothecene mycotoxin produced by Fusarium.
SERM.
c-Met inhibitor.
Water-soluble coenzyme, vitamin (B7) found in v...
A probe for cholesterol in biological membranes...
Peptide found in insects.
Zika Virus antigen
Dihydropyrazine found in Ligusticum walliichi. ...
Amino sugar, sorbitol derivative, used as a bul...
ITC precursor found in cruciferous vegetables.<...
HSP90 inhibitor.
PLK4 inhibitor.