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Voriconazole

Voriconazole

Product ID V5886
Cas No. 137234-62-9
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $77.80 In stock
100 mg $188.70 In stock
250 mg $301.70 In stock
1 g $943.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Voriconazole is a triazole antifungal compound developed specifically to target species of Aspergillus, although it displays broad spectrum activity against other fungi as well. Voriconazole inhibits 14α sterol demethylase (14αSD). This compound also exhibits immunomodulatory activity, as it increases levels of toll-like receptor 2 (TLR2) and TNF-α and stimulates translocation of NF-κB in monocytes.

Product Info

Cas No.

137234-62-9

Purity

≥98%

Formula

C16H14F3N5O

Formula Wt.

349.31

Chemical Name

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol

IUPAC Name

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2, 4-triazol-1-yl)butan-2-ol

Melting Point

127-130°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

V5886 MSDS PDF

Info Sheet

V5886 Info Sheet PDF

References

Thompson GR 3rd, Lewis JS 2nd. Pharmacology and clinical use of voriconazole. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):83-94. PMID: 19947892.

Simitsopoulou M, Roilides E, Paliogianni F, et al. Immunomodulatory effects of voriconazole on monocytes challenged with Aspergillus fumigatus: differential role of Toll-like receptors. Antimicrob Agents Chemother. 2008 Sep;52(9):3301-6. PMID: 18625774.

Varanasi NL, Baskaran I, Alangaden GJ, et al. Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agents. 2004 Jan;23(1):72-9. PMID: 14732317.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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  • This field is for validation purposes and should be left unchanged.

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