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α-Zearalanol is a mycotoxin that has structural similarity to estrogen and can bind to estrogen receptors. α-Zearalanol is one of the major metabolites of zearalenone, which is produced by several species of Fusarium and is known to induce many toxic effects.
| Cas No. | 26538-44-3 |
|---|---|
| Purity | ≥98% |
| Formula | C18H26O5 |
| Formula Wt. | 322.40 |
| Chemical Name | Alpha-Zearalenol |
| IUPAC Name | (7R,11R)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-trien-13-one |
| Synonym | MK-188; Zeranol; (-)-α-Zearalanol, alpha-Zearalanol; P1496 |
| Melting Point | 180-185°C |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Tatay E, Espin S, Garcia-Fernandez AJ, et al. Estrogenic activity of zearalenone, α-Zearalenol and β-Zearalenol assessed using the E-screen assay in MCF-7 cells. Toxicol Mech Methods. 2018 May;28(4):239-242. PMID: 29057713.
Ben Salem I, Boussabbeh M, Pires Da Silva J, et al. SIRT1 protects cardiac cells against apoptosis induced by zearalenone or its metabolites α-Zearalenol and β-Zearalenol through an autophagy-dependent pathway. Toxicol Appl Pharmacol. 2017 Jan 1;314:82-90. PMID: 27889531.
