LKT Labs

Biochemicals for Life Science Research

(−)-Epicatechin Gallate

(−)-Epicatechin Gallate

Product ID E6232
Cas No. 1257-08-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $52.00 In stock
5 mg $150.00 In stock
25 mg $325.00 In stock
Bulk Quote

Quicklinks

Description

(-)-Epicatechin gallate (ECG) is a flavanol/catechin originally found in Camilla and other plan sources; it exhibits antioxidative, neuromodulatory, anticancer, and anti-inflammatory activities. ECG displays agonist activity at cannabinoid 1 (CB1) receptors. ECG also inhibits expression of FLT3 and decreases phosphorylation of p38 MAPK, Akt, and STAT5 in acute myelogenous leukemia (AML) cells, suppressing cell proliferation. In vitro, this compound inhibits LPS- or peptidoglycan-induced production of VEGF and expression of COX-2.

Product Info

Cas No.

1257-08-5
Purity

≥98%
Formula

C22H18O10
Formula Wt.

442.37
Chemical Name

3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4- dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2-H-1-benzopyran-3-yl ester
IUPAC Name

[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Synonym

ECG
Melting Point

218°C

Solubility

Soluble in water or alcohol.
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

E6232 MSDS PDF
Info Sheet

E6232 Info Sheet PDF
Brochures

Green Tea Flyer

Brochures

Natural Products Booklet

References

Nakanishi T, Mukai K, Hosokawa Y, et al. Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. Int Endod J. 2014 May 21. [Epub ahead of print]. PMID: 24847951.

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0147

    Calcium Folinate Pentahydrate

    Folate source co-administered with methotrexate...

    ≥95%
  • A0778

    ABT-737

    BH3 mimetic; Bcl-2, Bxl-xl, Bcl-w inhibitor.

    ≥98%
  • L0108

    Lacidipine

    Calcium channel blocker.

    ≥98%
  • A5061

    Ampalex

    Benzylpiperidine; AMPA potentiator.

    ≥98%
  • N5072

    NMS-1286937

    PLK1 inhibitor.

    ≥98%
  • N5770

    Norfloxacin Hydrochloride

    First generation fluoroquinolone antibiotic.

    ≥98%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • M4652

    MLN8237

    AurKA inhibitor.

    ≥98%
  • D1869

    Deracoxib

    NSAID; COX-2 inhibitor.

    ≥99%
  • N5778

    Notoginsenoside R1

    Triterpene saponin found in species of Panax.

    ≥98%
  • L1684

    Levonorgestrel

    Synthetic progestogen; contraceptive.

    ≥98%
  • C179603

    CEP-37440 Hydrochloride

    Inhibitor of FAK and ALK.

    ≥99%
  • O1078

    Octreotide Acetate

    Somatostatin analog, peptide; somatostatin agon...

    ≥95%
  • N5655

    Nonoxynol-9

    Nonoxynol surfactant.

    90-110%
  • L0076

    Latrunculin A

    Thiazolidine macrolide found in the Red Sea spo...
  • V0275

    [Arg8]-Vasotocin

    Peptide, oxytocin-vasopressin analog.

    ≥95%
  • R0249

    Ramipril

    ACE inhibitor.

    ≥98%
  • A4544

    Allyl Disulfide

    Organosulfur found in garlic.

    ≥98%
  • G0248

    (-)-Gambogic Acid

    Xanthone found in Garcinia hanburyi.

    ≥99%
  • C9876

    CYT-387

    JAK2 inhibitor.

    ≥98%