17-α-Ethynylestradiol

Name: 17-α-Ethynylestradiol
SKU: E7731
Availability: InStock

Product ID E7731

Cas No. 57-63-6, 77538-56-8, 406932-93-2, 1050678-65-3

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

17-α-ethynylestradiol is a synthetic estrogen receptor (ER) agonist clinically used in contraceptive medications. In pregnant rats, 17-α-ethynylestradiol decreases platelet activating factor acetylhydrolase activity, inducing premature birth. 17-α-ethynylestradiol also displays weak antioxidative activity in lipid peroxidation assays in liver microsomes. Both acute and chronic exposure of wildlife (particularly fish) to 17-α-ethynylestradiol leads to feminization of males (through the induction of vitellogenin production), inhibiting fertility.

Product Info

Cas No.	57-63-6, 77538-56-8, 406932-93-2, 1050678-65-3
Purity	≥99%
Formula	C₂₀H₂₄O₂
Formula Wt.	296.40
Chemical Name	(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
IUPAC Name	(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Synonym	Ethinylestradiol
Melting Point	182-183°C
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	E7731 MSDS PDF
Info Sheet	E7731 Info Sheet PDF

References

Kidd KA, Blanchfield PJ, Mills KH, et al. Collapse of a fish population after exposure to a synthetic estrogen. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8897-901. PMID: 17517636.

Schultz IR, Skillman A, Nicolas JM, et al. Short-term exposure to 17 alpha-ethynylestradiol decreases the fertility of sexually maturing male rainbow trout (Oncorhynchus mykiss). Environ Toxicol Chem. 2003 Jun;22(6):1272-80. PMID: 12785584.

Yasuda K, Furukawa M, Johnston JM. Effect of estrogens on plasma platelet-activating factor acetylhydrolase and the timing of parturition in the rat. Biol Reprod. 1996 Jan;54(1):224-9. PMID: 8838020.

Lacort M, Leal AM, Liza M, et al. Protective effect of estrogens and catecholestrogens against peroxidative membrane damage in vitro. Lipids. 1995 Feb;30(2):141-6. PMID: 7769970.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

17-α-Ethynylestradiol

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

4’-Bromoflavone

Sertraline Hydrochloride

PHT-427

Estrone

Metformin Hydrochloride

Theophylline

Lomustine

Fumonisin B2

GBR 12935 Dihydrochloride

Methyl Caffeate

TG101348

Flavokawain A

Vitamin E, Natural

Ebastine

Rotenone

Copper Bis-3,5-diisopropylsalicylate

Nociceptin

Dinaciclib

n-Butyl Analog of Paclitaxel

Hypaconitine

Footer