Description
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
Product Unit Size | Cost | Quantity | Stock |
---|
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
Cas No. | 63597-44-4 |
---|---|
Purity | ≥98% |
Formula | C36H56O8 |
Formula Wt. | 616.83 |
Chemical Name | 4-α-12-Tetradecanoyl phorbol-13-acetate |
IUPAC Name | [(1S,2S,6S,10S,11R,13S,14R,15R)-13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] tetradecanoate |
Synonym | 4-αPMA |
Solubility | Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. |
Appearance | White to off white powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Chahine M, Qu Y, Mancarella S, et al. Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis. Pflugers Arch. 2008 Feb;455(5):913-9. PMID: 17909852.
Tosco M, Orsenigo MN, Gastaldi G, et al. Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. Exp Physiol. 2002 Nov;87(6):653-62. PMID: 12530398.
Polyphenol found in various plants and foods.
Diterpene found in brewed, unfiltered coffee; F...
Shellfish toxin produced by dinoflagellates and...
Peptide; FRP1 antagonist.
Diterpene found in Taxus yunnanensis; microtubu...
Endogenous hormone and neurotransmitter involve...
CDK2 inhibitor.
Furocoumarin; voltage-gated Na+ channel blocker...
NSAID; COX-1/2 inhibitor.
Building block
SIRT inhibitor.
Nucleoside (thymidine) analog; DNA chain termin...
Calcium channel blocker.
NSAID; COX-2 inhibitor.
Vitamin A metabolite, differentiation inducer; ...
Vitamin E component
14-α demethylase inhibitor.
Diclofenac analog, NSAID; COX-2 inhibitor.
Diterpene alcohol, geranylgeranyl pyrophosphate...
Active isomer of epinephrine, endogenous hormon...