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5-Hydroxytryptophol

5-Hydroxytryptophol

Product ID H9812
Cas No. 154-02-9
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $71.50 In stock
25 mg $153.10 In stock
100 mg $357.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

5-hydroxytryptophol is a neuromodulatory analog of serotonin and melatonin found in the needles of the Pinus sylvestris tree, wine, and beer, and is also the sleep-inducing component of the ‘sleeping sickness’ initially produced by the Trypanosoma brucei parasite. This compound is often used as a biomarker for recent alcohol consumption is it remains in the body much longer than ethanol. 5-hydroxytryptophol exudes some hypnotic activity, inducing a short-lived sleep state, and marginal antioxidative properties, inhibiting oxidation of LDL in a developmental atherosclerosis model.

Product Info

Cas No.

154-02-9

Purity

≥98%

Formula

C10H11NO2

Formula Wt.

177.20

IUPAC Name

3-(2-hydroxyethyl)-1H-indol-5-ol

Synonym

2-(5-Hydroxy-3-indolyl)ethyl alcohol

Solubility

PBS to 0.3 mg/ml, ethanol to 30 mg/ml, DMSO to 30 mg/ml

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

H9812 MSDS PDF

Info Sheet

H9812 Info Sheet PDF

References

Beck O, Helander A. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72. PMID: 14984243.

Wang HX, Liu F, Ng TB. Examination of pineal indoles and 6-methoxy-2-benzoxazolinone for antioxidant and antimicrobial effects. Comp Biochem Physiol C Toxicol Pharmacol. 2001 Nov;130(3):379-88. PMID: 11701394.

Cornford EM, Bocash WD, Braun LD, et al. Journal of Clinical Investigation 1979;63(6):1241–8. PMID: 447842.

Feldstein A, Chang FH, Kucharski JM. Tryptophol, 5-hydroxytryptophol and 5-methoxytryptophol induced sleep in mice". Life Sciences 1970;9 (6):323–9. PMID: 5444013.

Custom Order

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