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7-Aminoactinomycin D

Product ID A4930
Cas No. 7240-37-1
Purity ≥97%
Product Unit SizeCostQuantityStock
1 mg $153.30 In stock
5 mg $767.20 In stock
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  • Description
  • Product Info
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

7-Aminoactinomycin D (7AAD) binds DNA sequences and is used in cellular assays to measure apoptosis and phagocytosis.

Product Info

Cas No.

7240-37-1

Purity

≥97%

Formula

C62H87N13O16

Formula Wt.

1270.43

Chemical Name

2,7-diamino-4,6-dimethyl-3-oxo-N,N'-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide

IUPAC Name

2,7-diamino-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12, 15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11, 14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide

Synonym

7-Amino-Actinomycin D 7-amino-AMD Actinomycin D, 7-amino-

Melting Point

250°C

Solubility

Soluble in ethanol

Appearance

Purple Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A4930 MSDS PDF

Info Sheet

A4930 Info Sheet PDF

References

Su YJ, Cheng TT, Chen CJ, et al. The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus. J Transl Med. 2013 Oct 19;11:261. PMID: 24138706.

Ortega E, Algarra I, Serrano MJ, et al. The use of 7-amino-actinomycin D in the analysis of Candida albicans phagocytosis and opsonization. J Immunol Methods. 2001 Jul 1;253(1-2):189-93. PMID: 11384680.

Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996 Mar 15;87(6):2244-51. PMID: 8630384.

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