Name: A-type Natriuretic Peptide (1-11), rat
SKU: A5460
Availability: InStock

Description

Atrial natriuretic peptide (ANP) is a cardiomodulatory peptide that binds the natriuretic peptide receptor type A (NPR-A), increasing levels of cGMP and activating cGMP-dependent kinases. ANP exhibits vasodilatory/hypotensive, diuretic, and natriuretic activities, increasing perfusion and decreasing blood pressure in several models. ANP may also exhibit anticancer benefit, targeting the Ras-MEK-ERK signaling pathway.

Product Info

Purity	≥95%
Formula	C₄₉H₈₄N₂₀O₁₅S
Formula Wt.	1225.40
Synonym	Atrial natriuretic peptide, ANP
Solubility	Soluble in water.

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

Info Sheet	A5460 Info Sheet PDF

References

Vesely DL. New anticancer agents: hormones made within the heart. Anticancer Res. 2012 Jul;32(7):2515-21. PMID: 22753708.

Woodard GE, Rosado JA. Natriuretic peptides in vascular physiology and pathology. Int Rev Cell Mol Biol. 2008;268:59-93. PMID: 18703404.

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A-type Natriuretic Peptide (1-11), rat

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