• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Adefovir Dipivoxil

Adefovir Dipivoxil

Product ID A1218
Cas No. 142340-99-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $71.50 In stock
50 mg $204.30 In stock
250 mg $612.70 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Adefovir dipivoxil is the diester form of adefovir, an antiviral prodrug that displays immunomodulatory activity. Adefovir is an acyclonucleotide analog that inhibits viral DNA polymerase, acting as a DNA chain terminator. Adefovir is primarily used to treat hepatitis B infection, but also displays activity against retroviruses. Adefovir decreases levels of Treg cells and increases levels of IL-4, IL-2, TNF-α, and IFN-γ. Additionally, this compound may show anti-arthritic activity as well, inhibiting production of NO and expression of RANTES and acting both as a prophylactic or a rescue treatment in animal models of adjuvant-induced arthritis.

Product Info

Cas No.

142340-99-6

Purity

≥98%

Formula

C20H32N5O8P

Formula Wt.

501.47

Chemical Name

[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate

IUPAC Name

[2-(6-aminopurin-9-yl)ethoxymethyl-(2, 2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate

Synonym

Hepsera, Preveon

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A1218 MSDS PDF

Info Sheet

A1218 Info Sheet PDF

References

Jiang Y, Li W, Yu L, et al. Enhancing the antihepatitis B virus immune response by adefovir dipivoxil and entecavir therapies. Cell Mol Immunol. 2011 Jan;8(1):75-82. PMID: 20921939

Rodriguez-Frias F, Jardi R, Schaper M, et al. Adefovir for chronic hepatitis B treatment: identification of virological markers linked to therapy response. Antivir Ther. 2008;13(8):991-9. PMID: 19195324.

Zídek Z, Franková D, Holý A. Chemokines, nitric oxide and antiarthritic effects of 9-(2-phosphonomethoxyethyl)adenine (Adefovir). Eur J Pharmacol. 1999 Jul 2;376(1-2):91-100. PMID: 10440094.

Neyts J, De Clercq E. Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication. Biochem Pharmacol. 1994 Jan 13;47(1):39-41. PMID: 8311844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E7579

    Estramustine Phosphate Disodium

    Nitrogen mustard and estradiol derivative; micr...

    ≥95%
  • R3221

    3-Formylrifamycin

    Rifamycin derivative, induces pore formation in...

    ≥98%
  • P9768

    Pyronaridine Tetraphosphate

    Hemantin inhibitor.

    ≥98%
  • P327212

    Pifithrin-α-cyclic Hydrobromide

    p53 inhibitor

    ≥98%
  • G1408

    GDC-0449

    Smo inhibitor.

    ≥98%
  • S164098

    Seco-rapamycin

    Rapamycin analog

    ≥73%
  • H000051

    H-151

    STING antagonist

    ≥99%
  • F5873

    Foscarnet Sodium Hydrate

    Metal ion chelator, viral DNA polymerase inhibi...

    ≥98%
  • A2077

    Afatinib

    EGFR inhibitor.

    ≥98%
  • E5201

    Enalapril Maleate

    ACE inhibitor.

    ≥98%
  • C0265

    Carnosic Acid

    Diterpene found in Rosmarinus.

    ≥98%
  • T2833

    1-Thio-β-D-glucose Tetraacetate

    Imaging agent; Maillard reaction inhibitor.

    ≥98%
  • S1845

    L-(+)-Selenomethionine

    Naturally occurring amino acid found in grains,...

    ≥98%
  • V1872

    Vesicular Stomatitis Virus Peptide

    Peptide fragment of VSV; LDLR agonist.

    ≥95%
  • C451338

    Clioquinol

    Antifungal agent with neuroprotective activity....

    ≥98%
  • S6235

    Spironolactone

    Mineralocorticoid, aldosterone, AR antagonist, ...

    ≥97%
  • J766160

    JTE907

    Selective Cannabinoid receptor 2(CB2) inverse a...

    ≥98%
  • E5178

    Emtricitabine

    Nucleoside (cytidine) analog; RT and telomerase...

    ≥98%
  • O9257

    16-Oxokahweol

    Synthetic kahweol derivative.

    ≥95%
  • O4556

    Olomoucine

    Purine derivative; CDK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only