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Amikacin Disulfate

Amikacin Disulfate

Product ID A5132
Cas No. 39831-55-5
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $61.10 In stock
1 g $142.90 In stock
5 g $408.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amikacin is an aminoglycoside antibiotic that exhibits antibacterial efficacy against gram negative bacteria. Amikacin binds the 30S ribosomal subunit, preventing translation.

Product Info

Cas No.

39831-55-5

Purity

≥98%

Formula

C22H43N5O13 • 2H2SO4

Formula Wt.

781.76

Chemical Name

O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [6-amino-6-deoxy-α-D-glucopyranosyl-(1->4)]-N1- [(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D- streptamine sulfate

IUPAC Name

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3, 5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S, 6R)-6-(aminomethyl)-3,4, 5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid

Synonym

Amikacin sulfate, Amikin, Biklin, Lukadin, Mikavir, Novamin, Pierami

Melting Point

220-230°C(dec.)

Solubility

Soluble in water (50mg/mL). Insolulble in acetone and water. DMSO <1 mg/mL.

Appearance

White or Almost White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5132 MSDS PDF

Info Sheet

A5132 Info Sheet PDF

References

Barza M, Scheife RT. Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics--part 4: aminoglycosides. Am J Hosp Pharm. 1977 Jul;34(7):723-37. PMID: 407790.

Kawaguchi H. Discovery, chemistry, and activity of amikacin. J Infect Dis. 1976 Nov;134 SUPPL:S242-8. PMID: 825583.

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274.

Custom Order

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