• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Bergenin

Bergenin

Product ID B1769
Cas No. 477-90-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $173.60 In stock
5 mg $628.50 In stock
10 mg $917.80 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bergenin is a trihydroxybenzoic acid glycoside found in Bergenia and other plant sources. Bergenin exhibits immunosuppressive, anti-inflammatory, anti-parasitic, antimalarial, analgesic, antinociceptive, antioxidative, anti-diabetic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. In vivo, bergenin downregulates expression of NF-κB and IKKβ, decreases IgG levels, cytokine release, and other immune response mediators, and suppresses development of edema. In vitro and in vivo, bergenin inhibits growth of Plasmodium. In other animal models, this compound inhibits mechanical hyperalgesia. In diabetic rats, bergenin decreases levels of blood glucose, total cholesterol, and LDL and increases levels of HDL, superoxide dismutase, and catalase. Additionally, bergenin inhibits tumor development induced by TPA and DMBA.

Product Info

Cas No.

477-90-7

Purity

≥98%

Formula

C14H16O9

Formula Wt.

328.27

IUPAC Name

3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a, 10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one;hydrate

Melting Point

237-240°C

Solubility

Slightly soluble in DMSO, methanol. Insoluble in water, ethanol.

Appearance

White Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B1769 MSDS PDF

Info Sheet

B1769 Info Sheet PDF

References

Jain SK, Singh S, Khajuria A, et al. Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity. J Med Chem. 2014 Aug 28;57(16):7085-97. PMID: 25111439.

Liang J, Li Y, Liu X, et al. In vivo and in vitro antimalarial activity of bergenin. Biomed Rep. 2014 Mar;2(2):260-264. PMID: 24649107.

Zhang J, Nishimoto Y, Tokuda H, et al. Cancer chemopreventive effect of bergenin from Peltophorum pterocarpum wood. Chem Biodivers. 2013 Oct;10(10):1866-75. PMID: 24130029.

Kumar R, Patel DK, Prasad SK, et al. Type 2 antidiabetic activity of bergenin from the roots of Caesalpinia digyna Rottler. Fitoterapia. 2012 Mar;83(2):395-401. PMID: 22178680.

de Oliveira CM, Nonato FR, de Lima FO, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8. Erratum in: J Nat Prod. 2012 Feb 24;75(2):305. PMID: 21939182.

Wang X, Tang S, Zhai H, et al. Studies on anti-tumor metastatic constituents from Ardisia Crenata. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):881-5. PMID: 21761727.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%
  • G8850

    GW-5074

    c-Raf inhibitor.

    ≥98%
  • T6830

    Triadimefon

    Neurotoxin, mutagen.

    ≥98%
  • T165133

    Tedizolid Phosphate

    Effective against gram-positive pathogens

    ≥98%
  • P1765

    Peptide Standard 1

    For use in amino acid analysis.

    ≥95%
  • C0261

    Captopril

    ACE inhibitor.

    ≥98%
  • A9602

    Azacitidine

    Nucleoside (cytidine) analog; DNMT inhibitor, p...

    ≥98%
  • V3213

    Vidarabine Monophosphate

    Nucleoside (adenosine) analog found in Tethyra ...

    ≥98.0%
  • V3345

    Vildagliptin

    DPP4 inhibitor.

    ≥98%
  • S8244

    Sulbactam

    β-lactamase inhibitor.

    ≥98%
  • A0776

    ABT-199

    BH3 mimetic; Bcl-2 inhibitor.

    ≥99%
  • F1654

    Fenoldopam Mesylate

    Benzazepine derivative; D1 partial agonist, pot...

    ≥98%
  • E6814

    Erdosteine

    Thiol derivative, antioxidant.

    ≥98%
  • S8345

    S-(−)-Sulpiride

    GHB agonist, D2/3 antagonist.

    ≥99%
  • I1418

    Idebenone

    Synthetic quinone CoQ analog, promotes mitochon...

    ≥98%
  • S3476

    Sitagliptin Phosphate Monohydrate

    DPP4 inhibitor.

    ≥98%
  • S7769

    Streptomycin Sulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • A6264

    Apramycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • D3330

    Dihydrotanshinone

    Found in Salvia; fatty acid synthase and AChE i...

    ≥90%
  • S1843

    L-Selectin

    Endogenous adhesion molecule, binds PKC, calmod...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only