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Betulin

Betulin

Product ID B1977
Cas No. 473-98-3
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $92.00 In stock
1 g $183.60 In stock
5 g $796.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Betulin is a pentacyclic triterpene found in birch bark. This compound can induce apoptosis and inhibit angiogenesis, lending it a wide variety of functions, including anticancer, antiviral, anti-inflammatory, anti-fibrotic, antioxidative, and antibacterial roles. Betulin is hepatoprotective as well, as it suppresses symptoms of ethanol-induced fatty liver by inhibiting acidophilic necrosis; it also prevents liver fibrosis by inhibiting production and migration of ROS.

Product Info

Cas No.

473-98-3

Purity

≥98%

Formula

C30H50O2

Formula Wt.

442.72

Chemical Name

Lup-20(29)-ene-3β,28-diol

IUPAC Name

(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8, 8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13, 13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol

Melting Point

256–257°C

Solubility

Soluble in DMF (2.5 mg/mL), DMSO (2 mg/mL), ethanol (5 mg/mL). Slightly soluble in chloroform, methanol.

Appearance

White powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B1977 MSDS PDF

Info Sheet

B1977 Info Sheet PDF

References

Wan Y, Jiang S, Lian LH, et al. Betulinic acid and betulin ameliorate acute ethanol-induced fatty liver via TLR4 and STAT3 in vivo and in vitro. Int Immunopharmacol. 2013 Jun 28;17(2):184-190. [Epub ahead of print] PMID: 23816536.

Jonnalagadda SC, Corsello MA, Sleet CE. Betulin-Betulinic Acid Natural Product Based Analogs as Anti-Cancer Agents. Anticancer Agents Med Chem. 2013 Jun 11. [Epub ahead of print] PubMed PMID: 23848199.

Szuster-Ciesielska A, Plewka K, Kandefer-Szerszeń M. Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells. Pharmacol Rep. 2011;63(5):1109-23. PMID: 22180353.

Custom Order

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