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Carboplatin

Carboplatin

Product ID C0171
Cas No. 41575-94-4
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $61.10 In stock
100 mg $180.30 In stock
250 mg $390.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Carboplatin is a platinum-based cross-linking agent that exhibits immunomodulatory and anticancer chemotherapeutic activities. Carboplatin binds DNA with slower kinetics than other platinum drugs, inhibiting DNA transcription and replication; it is clinically used to treat various cancers. Carboplatin also modulates STAT signaling and release of HMGB-1.

Product Info

Cas No.

41575-94-4

Purity

≥99%

Formula

C6H12N2O4Pt

Formula Wt.

371.25

Chemical Name

(SP-4-2)-Diammine-[1,1-cyclobutanedi(carboxylato- κO)(2-)]platinum

IUPAC Name

azane;cyclobutane-1,1-dicarboxylate;platinum(2+)

Synonym

Paraplati, cis-Diammine[1,1 cyclobutane dicarboxylato] platinum

Melting Point

228-230°C

Solubility

Soluble in water (10 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0171 MSDS PDF

Info Sheet

C0171 Info Sheet PDF

Brochures

JAK/STAT Flyer

References

Hato SV, Khong A, de Vries IJ, et al. Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics. Clin Cancer Res. 2014 Jun 1;20(11):2831-7. PMID: 24879823.

Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells. J Am Chem Soc. 2010 Jun 2;132(21):7429-35. PMID: 20443565.

Custom Order

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