LKT Labs

Biochemicals for Life Science Research

Cetrorelix Acetate

Cetrorelix Acetate

Product ID C1879
Cas No. 130143-01-0
Purity ≥95%
Product Unit SizeCostQuantityStock
50 mg $1,968.00 Please Inquire
100 mg $2,679.00 Please Inquire
Bulk Quote

Quicklinks

Description

Cetrorelix is a gonadotropin-releasing hormone (GnRH) analog that inhibits LHRH and GnRH. Cetrorelix exhibits anti-inflammatory activity and has been used clinically as a treatment for infertility due to its suppression of FSH and LH levels. In animal models of benign prostatic hyperplasia (BPH), cetrorelix decreases levels of inflammatory cytokines and growth factors, decreasing prostate size and weight. Additionally, cetrorelix decreases levels of Bax, caspase 3, and cytochrome c, inhibiting chemotherapy-induced mitochondria-dependent apoptosis in granulosa cells in vivo.

Product Info

Cas No.

130143-01-0
Purity

≥95%
Formula

C70H92N17O14
Formula Wt.

1431.06
IUPAC Name

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[ (2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl) propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl] amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl] amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N- [(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Synonym

Cetrelix Acetate, Cetrorenlin Acetate
Solubility

Soluble in DMSO.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

C1879 MSDS PDF
Info Sheet

C1879 Info Sheet PDF

References

Rick FG, Schally AV, Block NL, et al. LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Prostate. 2011 May 15;71(7):736-47. PMID: 20945403.

Zhao XJ, Huang YH, Yu YC, et al. GnRH antagonist cetrorelix inhibits mitochondria-dependent apoptosis triggered by chemotherapy in granulosa cells of rats. Gynecol Oncol. 2010 Jul;118(1):69-75. PMID: 20417958.

Reissmann T, Felberbaum R, Diedrich K, et al. Development and applications of luteinizing hormone-releasing hormone antagonists in the treatment of infertility: an overview. Hum Reprod. 1995 Aug;10(8):1974-81. PMID: 8567825.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G3554

    Ginsenoside Rb3

    Triterpene saponin found in species of Panax.

    ≥98%
  • V2792

    VGX-1027

    TLR4 inhibitor.

    ≥98%
  • I5072

    Imazalil

    Triazole; 14-α demethylase and aromatase inhib...

    ≥95%, titration; ≥70%, HPLC
  • T3036

    Thienylhexyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥97%
  • M324081

    Micafungin Sodium

    Echinocandin antifungal

    ≥98%
  • P982691

    Pyridostatin Trifluoroacetate Salt

    G-quadruplex ligand; DNA breakage inducer.

    ≥95%
  • P2100

    PF-06447475

    LRRK2 inhibitor.

    ≥98%
  • A528251

    Angiotensin I/II (1-7)(DP-7)

    Peptide fragment

    ≥95%
  • C0367

    S-(−)-Carbidopa Monohydrate

    Hydrazine; L-amino acid decarboxylase inhibitor...

    ≥98%
  • N1757

    Neostigmine Bromide

    AChE inhibitor.

    ≥92%
  • C5680

    Coumestrol

    Phytoestrogen found in various plant sources; E...

    ≥97%
  • B4518

    Bleomycin Sulfate

    Mixture of glycopeptide bleomycin sulfate salts...

    ≥90%
  • R5878

    Rotenone

    Micronuclei formation inducer, antimitotic, oxi...

    ≥97%
  • I5208

    INCB-28060

    c-MET inhibitor.

    ≥98%
  • A7658

    Atorvastatin Calcium Trihydrate

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • N5778

    Notoginsenoside R1

    Triterpene saponin found in species of Panax.

    ≥98%
  • M1752

    Men 10376

    Peptide; NK2 antagonist.

    ≥95%
  • C4510

    Climbazole

    14-α demethylase inhibitor.

    ≥99%
  • J6400

    (+)-JQ-1

    Triazolothienodiazepine; BRD inhibitor.

    ≥99%
  • A9662

    AZ-628

    B-Raf and c-Raf inhibitor.

    ≥96%