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Chaetoglobosin A is a cytochalasan type alkaloid with potent antifungal activity against Rhizopus stolonifer and Coniothyrium diplodiella. It is a secondary metabolite produced by the endophytic fungus Chaetomium globosum No. 04. Cytochalasans are known to exhibit strong cytotoxicity on various human cancer cell lines.
| Cas No. | 50335-03-0 |
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| Purity | ≥99% |
| Formula | C32H36N2O5 |
| Formula Wt. | 528.64 |
| Chemical Name | (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-7-Hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-4,7,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-8,11,12(13H)-trione |
| IUPAC Name | (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-7-Hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-4,7,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-8,11,12(13H)-trione |
| Melting Point | 168-170°C |
| Solubility | Soluble in DMSO, ethanol, methanol. |
| Appearance | Yellow powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| Info Sheet |
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Zhang G, Zhang Y, Qin J, et al. Antifungal metabolites produced by Chaeyomium globosum No. 04, an endophytic fungus isolated from Ginko biloba. Indian J Microbiol. 2013 Jun; 53(2): 175-180. PMID: 24426105.
