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Chromostatin, cow

Product ID C2971
Cas No. 133633-11-1
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $265.90 Please Inquire
1 mg $422.70 Please Inquire
2.5 mg $845.60 Please Inquire
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  • Product Info
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  • Description
  • Product Info
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  • Downloads
  • References
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Description

Chromostatin is a peptide fragment representing chromogranin A (124-143). Chromostatin exhibits cardiomodulatory activity, inhibiting vasoconstriction in thoracic arteries and saphenous veins induced by K+, norepinephrine, and endothelin-1. Additionally, chromostatin inhibits catecholamine secretion in chromaffin cells through the activation of protein phosphatase 2A (PP2A).

Product Info

Cas No.

133633-11-1

Purity

≥95%

Formula

C78H120N24O35

Formula Wt.

1953.97

Synonym

Chromogranin A (124-143); CgA; Pituitary Secretory Protein I; SP-I; CHGA; Cromostatin-20; CST.

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C2971 MSDS PDF

Info Sheet

C2971 Info Sheet PDF

References

Garcia GE, Gabbai FB, O'Connor DT, et al. Does chromostatin influence catecholamine release or blood pressure in vivo? Peptides. 1994 Jan;15(1):195-7. PMID: 8015978.

Aardal S, Galindo E, Aunis D, et al. Human chromostatin inhibits endothelin-1-induced contractures in human blood vessels. Regul Pept. 1993 Aug 13;47(1):25-32. PMID: 8210519.

Galindo E, Zwiller J, Bader MF, et al. Chromostatin inhibits catecholamine secretion in adrenal chromaffin cells by activating a protein phosphatase. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7398-402. PMID: 1323834.

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