• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ciclesonide

Ciclesonide

Product ID C324091
Cas No. 126544-47-6
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $99.80 In stock
25 mg $288.80 In stock
100 mg $892.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation.

Product Info

Cas No.

126544-47-6

Purity

≥98%

Formula

C32H44O7

Formula Wt.

540.7

Chemical Name

(R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate

IUPAC Name

[2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 2-methylpropanoate

Synonym

Alvesco; Omnaris; Zetonna; RPR251526

Solubility

Insoluble in water. Soluble in EtOH and DMSO.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

Info Sheet

C324091 Info Sheet PDF

References

H. Kimura, H. Kurusu, M. Sada, et al. Molecular pharmacology of ciclesonide against SARS-CoV-2. J Allergy Clin Immunol. (2020) 146:330-331.

G. Tsuji, S. Nakajima, K. Watashi, et al. Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication. J Pharmacol Sci. (2022) 149:81-84.

S. Matsuyama, M. Kawase, N. Nao, The Inhaled Steroid Ciclesonide Blocks SARS-CoV-2 RNA Replication by Targeting the Viral Replication-Transcription Complex in Cultured Cells. J Virol. (2020) (95)1648-20.

H. S. Choi, S-L Kim, J-H Kim and D-S Lee. The FDA-Approved Anti-Asthma Medicine Ciclesonide Inhibits Lung Cancer Stem Cells through Hedgehog Signaling-Mediated SOX2 Regulation. Int J Mol Sci. (2020) 21:1014.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E8419

    Everolimus

    mTORC1 inhibitor.

    ≥98%
  • T2404

    TG101348

    JAK2 inhibitor.

    ≥98%
  • M3321

    Mifepristone

    Synthetic steroid, contraceptive; PR and glucoc...

    ≥98%
  • C3449

    Clodronate Disodium Tetrahydrate

    Non-nitrogen bisphosphonate; mitochondrial ATP/...

    ≥98%
  • N8760

    NVP-TAE684

    ALK, c-Fes, LRRK2 inhibitor.

    ≥98%
  • G1721

    Gefitinib

    EGFR inhibitor.

    ≥98%
  • R8206

    Rubescensin A

    Diterpene originally found in Rabdosia.

    ≥93%
  • G0146

    Galanin, human

    Endogenous neuropeptide, involved in nociceptio...

    ≥98%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.

    ≥98%
  • H1894

    Hexestrol

    Synthetic catechol; ER agonist, microtubule pol...

    ≥98%
  • C9612

    Cyclosporin C

    Cyclosporin metabolite; weak calmodulin inhibit...

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • L3250

    D-Limonene

    Terpene found in the rind of various citrus fru...

    ≥97%
  • C2468

    β-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥98%
  • C4557

    Clofibrate

    Fibrate; PPARα agonist.

    ≥99%
  • I7258

    Isoflurane

    Ca2+ ATPase and ATP-sensitive K+ channel activa...

    ≥98%
  • T6934

    Trimebutine Maleate

    L-type Ca2+ channel blocker, BK K+ channel modu...

    ≥96%
  • P0145

    Palmitoyl-D,L-carnitine

    Long chain acylcarnitine involved in fatty acid...

    ≥98%
  • G1749

    Gemfibrozil

    Fibrate; PPARα agonist, enoyl-CoA reductase in...

    ≥98%
  • O783743

    OTSSP167 Hydrochloride

    MELK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only