• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Cinacalcet Hydrochloride

Cinacalcet Hydrochloride

Product ID C3352
Cas No. 364782-34-3
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $60.90 In stock
25 mg $194.30 In stock
100 mg $446.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cinacalcet is an agonist at Ca2+-sensing receptors that is clinically used to treat secondary hyperparathyroidism with chronic kidney disease. Cinacalcet also displays anti-fibrotic activity. This compound decreases levels of parathyroid hormone (PTH), increases adiponectin secretion, and lowers oxidative stress. This compound increases sensitivity of Ca2+-sensing receptors to serum Ca2+ levels. In vivo, cinacalcet decreases renal epithelial-to-mesenchymal transition (EMT) and prevents the development of renal fibrosis.

Product Info

Cas No.

364782-34-3

Purity

≥99%

Formula

C22H22F3N • HCl

Formula Wt.

393.87

IUPAC Name

N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine hydrochloride (1:1)

Solubility

100mM in DMSO

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C3352 MSDS PDF

Info Sheet

C3352 Info Sheet PDF

References

Kuczera P, Adamczak M, Machnik G, et al. Treatment with Cinacalcet Increases Plasma Adiponectin Concentration in Hemodialysed Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism. Endocr Pract. 2015 Mar 18:1-22. [Epub ahead of print]. PMID: 25786554.

Wu M, Tang RN, Liu H, et al. Cinacalcet attenuates the renal endothelial-to-mesenchymal transition in rats with adenine-induced renal failure. Am J Physiol Renal Physiol. 2014 Jan 1;306(1):F138-46. PMID: 24154694.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A0817

    D,L-1’-Acetoxychavicol acetate

    TRPA1 agonist, xanthine oxidase inhibitor.

    ≥98%
  • A4930

    7-Aminoactinomycin D

    Actinomycin derivative used to study apoptosis ...

    ≥98%
  • I5830

    Iohexol

    Low osmolarity contrast agent used for imaging ...

    ≥98%
  • A4547

    Alloxan Monohydrate

    Pyrimidine, glucose analog, used to induce diab...

    ≥98%
  • P2918

    Phenylethyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • B4402

    Blasticidin S Hydrochloride

    Protein translation inhibitor.

    ≥98%
  • P3018

    Phellodendrine

    Quaternary base alkaloid found in Phellodendron...

    ≥98%
  • L960002

    LY-294002 Hydrochloride

    Inhibitor of PI3K.

    ≥98%
  • B1753

    Benfotiamine

    Thiamine/vitamin B derivative, antioxidant.

    ≥98%
  • P2502

    Phenethyl Glucosinolate Potassium

    Found in cruciferous vegetables.

    ≥97%
  • A745817

    Asunaprevir

    Antiviral againt SARS-CoV-2

    ≥98%
  • B8262

    Bupivacaine Hydrochloride Monohydrate

    Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3...

    ≥98%
  • P3210

    Picoplatin

    Pt-based DNA cross-linker.

    ≥98%
  • R3221

    3-Formylrifamycin

    Rifamycin derivative, induces pore formation in...

    ≥98%
  • C4657

    Clotrimazole

    Imidazole; 14-α demethylase, H+/K+ ATPase, Na+...

    ≥97%
  • P2012

    PF-04217903

    Triazolopyrazine; c-MET inhibitor.

    ≥98%
  • L9800

    LY-364947

    ALK5 (activin-like) inhibitor.

    ≥98%
  • T5761

    Topotecan Hydrochloride

    Captothecin derivative; topoisomerase I inhibit...

    ≥97%
  • C2816

    Cheirolin

    Naturally produced ITC, sulfonyl analog of sulf...

    ≥97%
  • E7329

    Ethoxyquin

    Quinoline, food preservative; HSP90 inhibitor.<...

    ≥90%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only