• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Cinnarizine

Cinnarizine

Product ID C3251
Cas No. 298-57-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $56.50 In stock
100 g $283.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cinnarizine is an inhibitor of L-type voltage-gated Ca2+ channels that is clinically used to treat migraine and vertigo. Cinnarizine exhibits anticonvulsant/antiepileptic activity in combination with other therapies in animal models. This compound also inhibits D2 receptors, suppressing stimulant-induced locomotor activity, and acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.

298-57-7

Purity

≥98%

Formula

C26H28N2

Formula Wt.

368.51

Chemical Name

1-benzhydryl-4-cinnamyl-piperazine

IUPAC Name

1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine

Synonym

Aplactan, Aplexal, Apotomin, Artate, Carecin, Cerebolan, 1-trans-Cinnamyl-4-diphenylmethylpiperazine

Melting Point

118-122°C

Solubility

Practically insoluble in water. Soluble in dichloromethane or ether. Slightly soluble in methanol.

Appearance

White or Almost-White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C3251 MSDS PDF

Info Sheet

C3251 Info Sheet PDF

References

Taghdiri F, Togha M, Razeghi Jahromi S, et al. Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study. Springerplus. 2014 May 7;3:231. PMID: 24834377.

Brahmane RI, Wanmali VV, Pathak SS, et al. Role of cinnarizine and nifedipine on anticonvulsant effect of sodium valproate and carbamazepine in maximal electroshock and pentylenetetrazole model of seizures in mice. J Pharmacol Pharmacother. 2010 Jul;1(2):78-81. PMID: 21350614.

Dall'Igna OP, Tort AB, Souza DO, et al. Cinnarizine has an atypical antipsychotic profile in animal models of psychosis. J Psychopharmacol. 2005 Jul;19(4):342-6. PMID: 15982988.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0099

    10-Deacetylbaccatin-III

    Diterpene found in Taxus.

    ≥98%
  • D3428

    Dihydrochelerythrine

    Benzophenanthridine alkaloid found in Garcinia....

    ≥98%
  • H9661

    Hypocrellin A

    Prevents MHC II antigen presentation.

    ≥77%, contains ~16% B
  • S1971

    Sertraline Hydrochloride

    FIASMA, SERT and DAT inhibitor, α1-adrenergic ...

    ≥98%
  • U8000

    U-74389G

    Antioxidant shown to improve renal function.

    ≥95%
  • F1655

    Fenoprofen Calcium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥97%
  • Z1970

    Zerumbone

    Cyclic sesquiterpene found in ginger root; pote...

    ≥99%
  • T1777

    S,S-(+)-Tetrandrine

    Benzylisoquinoline alkaloid originally found in...

    ≥98%
  • G124088

    GDC-1971

    SHP2 inhibitor

    ≥99%
  • E6376

    Eptifibatide

    Glycoprotein IIb/IIIa inhibitor.

    ≥98%
  • C9709

    Cycloheximide

    Protein synthesis inhibitor, used to measure pr...

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • E6782

    S-Equol

    Isoflavone, phytoestrogen found in soy; ER agon...

    ≥99%
  • C0800

    C59

    PORCN inhibitor.

    ≥98%
  • C2960

    Chondroitin Sulfate, cow

    Polyanionic sulfated glycosaminoglycan, encogen...

    ≥90%
  • P1969

    Perifosine

    Alkylphospholipid analog; Akt inhibitor.

    ≥98%
  • B6809

    [DPhe7]-Bradykinin

    Natriuretic, vasodilatory peptide, bradykinin a...

    ≥95%
  • H1662

    HER2/neu (654-662) GP2

    Peptide fragment of HER2/neu/erbB2 receptor.

    ≥95%
  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • T0109

    13-Acetyl-9-dihydrobaccatin-III

    Found in Taxus, starting material for synthesis...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only