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CTAP

Product ID C7602
Cas No. 103429-32-9
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $163.20 Please Inquire
1 mg $278.20 Please Inquire
2.5 mg $489.60 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

CTAP is an antagonist at μ-opioid receptors (μORs) that exhibits neuromodulatory activity. CTAP prevents reinstatement of drug seeking in animal models of ethanol addiction. CTAP also prevents opioid-induced decreases in inflammatory cytokine release in animal models of intestinal ischemia/reperfusion. Additionally, CTAP inhibits opioid-induced analgesia in animal models of colorectal distension.

Product Info

Cas No.

103429-32-9

Purity

≥95%

Formula

C51H67N13O11S

Formula Wt.

1102.33

IUPAC Name

(4R,7S,10S,13S,16S,19R)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2S)-2-amino-3-phenylpropanoyl]amino]-10-[3-(diaminomethylideneamino)propyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-3,3-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

Synonym

Connective tissue-activating peptide.

Solubility

Soluble in water (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C7602 MSDS PDF

Info Sheet

C7602 Info Sheet PDF

References

Perry CJ, McNally GP. A role for the ventral pallidum in context-induced and primed reinstatement of alcohol seeking. Eur J Neurosci. 2013 Sep;38(5):2762-73. PMID: 23773238.

Saccani F, Anselmi L, Jaramillo I, et al. Protective role of μ opioid receptor activation in intestinal inflammation induced by mesenteric ischemia/reperfusion in mice. J Neurosci Res. 2012 Nov;90(11):2146-53. PMID: 22806643.

Distrutti E, Cipriani S, Renga B, et al. Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain. Mol Pain. 2010 Jun 11;6:36. PMID: 20540729.

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