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Cyclosporin C

Cyclosporin C

Product ID C9612
Cas No. 59787-61-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $102.00 In stock
5 mg $408.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cyclosporin C is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin C exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and in vivo. This compound also exhibits antifungal activity against filamentous phytopathogenic fungi.

Product Info

Cas No.

59787-61-0

Purity

≥98%

Formula

C62H111N11O13

Formula Wt.

1218.61

IUPAC Name

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-[(1R)-1-hydroxyethyl]-33-[(E, 1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25, 28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1, 4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17, 20,23,26,29,32-undecone

Synonym

Thr2-cyclosporine

Melting Point

152-155°C

Solubility

Soluble in methanol, ethanol, acetone, ether or chloroform.

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C9612 MSDS PDF

Info Sheet

C9612 Info Sheet PDF

References

Moussaïf M, Jacques P, Schaarwächter P, et al. Cyclosporin C is the main antifungal compound produced by Acremonium luzulae. Appl Environ Microbiol. 1997 May;63(5):1739-43. PMID: 9143111.

Uadia PO, Ezeamuzie IC, Ladan MJ, et al. Antimalarial activity of cyclosporins A, C and D. Afr J Med Med Sci. 1994 Mar;23(1):47-51. PMID: 7839946.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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