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D-Tetrahydropalmatine is an alkaloid originally found in Corydalis. D-Tetrahydropalmatine inhibits D1 receptors, but unlike its optical L isomer, has no affinity for D2 receptors. This compound also inhibits the organic cation transporter 1.
| Cas No. | 2934-97-6 |
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| Purity | ≥99% |
| Formula | C21H25NO4 |
| Formula Wt. | 355.43 |
| Chemical Name | (13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| IUPAC Name | (13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| Synonym | Rotundine |
| Appearance | White to off white powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Tu M, Sun S, Wang K, et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity. Toxicology. 2013 Sep 15;311(3):225-30. PMID: 23831208.
Xu SX, Yu LP, Han YR, et al. Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo Yao Li Xue Bao. 1989 Mar;10(2):104-10. PMID: 2530755.