Description
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
Product Unit Size | Cost | Quantity | Stock |
---|
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
Cas No. | 4342-03-4 |
---|---|
Purity | ≥98% |
Formula | C6H10N6O |
Formula Wt. | 182.18 |
Chemical Name | 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4- carboxamide |
IUPAC Name | (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
Synonym | Dacatic, DTIC-Dome, Deticene |
Melting Point | 205°C |
Solubility | Slightly soluble in water and alcohol. |
Appearance | Light pink powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Gallamini A, Di Raimondo F, La Nasa G, et al. Standard therapies versus novel therapies in Hodgkin lymphoma. Immunol Lett. 2013 Sep-Oct;155(1-2):56-9. PMID: 24140162.
Koprowska K, Czyż M. Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities. Postepy Hig Med Dosw (Online). 2011 Nov 23;65:734-51. PMID: 22173438.
Diaminoquinazoline derivative.
Nitroimidazole, binds DNA; nucleic acid synthes...
MGMT inhibitor.
Efflux pump inhibitor
Sesquiterpene alcohol found in various essentia...
Methimazole prodrug; thyroid peroxidase inhibit...
Triterpene saponin found in species of Panax.
Mycotoxin contaminant found in cereal grains.
Effective against gram-positive pathogens
Microtubule polymerization inhibitor.
1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...
Long-chain 3-ketoacyl-CoA thiolase inhibitor, p...
Mixture of pyrantel, a thiophene, and pamoic ac...
Found in Aristolochia and Radix; PLA2 inhibitor...
NSAID; NMDA inverse agonist, T-type Ca2+ and Cl...
ITC, sulforaphane analog.
Furocoumarin; voltage-gated Na+ channel blocker...
Peptide found in crustaceans; PKA activator.
Natriuretic, vasodilatory peptide; B1/2 agonist...
Pim-1 inhibitor.