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Deslorelin Acetate

Product ID D1775
Cas No. 57773-65-6
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $200.20 Please Inquire
5 mg $344.90 Please Inquire
10 mg $519.20 Please Inquire
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  • Product Info
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  • Description
  • Product Info
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Description

Deslorelin is a gonadotropin-releasing hormone (GnRH) agonist that is used to control fertility and treat benign prostatic hyperplasia (BPH) in veterinary medicine. Deslorelin decreases expression of GnRH receptors and levels of testosterone, decreasing the volume of the testes and prostate in many male animal models. In male animals, deslorelin is used to instill sterility. In female animals, this peptide is used to induce estrous.

Product Info

Cas No.

57773-65-6

Purity

≥95%

Formula

C64H83N17O12

Formula Wt.

1282.47

IUPAC Name

N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2- (ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1- oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4- hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino] -3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1- oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Solubility

Insoluble in water. Soluble in DMSO (12 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D1775 MSDS PDF

Info Sheet

D1775 Info Sheet PDF

References

Marino G, Rizzo S, Quartuccio M, et al. Deslorelin Implants in Pre-pubertal Female Dogs: Short- and Long-Term Effects on the Genital Tract. Reprod Domest Anim. 2014 Apr;49(2):297-301. PMID: 24467617.

Goericke-Pesch S, Georgiev P, Fasulkov I, et al. Basal testosterone concentrations after the application of a slow-release GnRH agonist implant are associated with a loss of response to buserelin, a short-term GnRH agonist, in the tom cat. Theriogenology. 2013 Jul 1;80(1):65-9. PMID: 23622940.

Polisca A, Orlandi R, Troisi A, et al. Clinical efficacy of the GnRH agonist (deslorelin) in dogs affected by benign prostatic hyperplasia and evaluation of prostatic blood flow by Doppler ultrasound. Reprod Domest Anim. 2013 Aug;48(4):673-80. PMID: 23320475.

Wolf T, Meyer H, Kutzler M. Litter size response to oestrous induction with deslorelin (Ovuplant®) in dogs. Reprod Domest Anim. 2012 Dec;47 Suppl 6:387-8. PMID: 23279545.

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