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Docetaxel

Docetaxel

Product ID D5709
Cas No. 114977-28-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $68.10 In stock
10 mg $122.70 In stock
25 mg $299.90 In stock
100 mg $817.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Docetaxel is a taxane that exhibits anticancer chemotherapeutic activity. Docetaxel is a semi-synthetic analog of taxol that displays a similar mechanism of action, acting as an antimitotic by inhibiting microtubule depolymerization.

Product Info

Cas No.

114977-28-5

Purity

≥98%

Formula

C43H53NO14

Formula Wt.

807.89

Chemical Name

(αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic acid (2aR,4S,4aS,6R,9S,- 11S,12S,12aR,12bS)-12b-(acetyloxy)-12(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11- trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonym

N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, Taxotere

Melting Point

186-190°C

Solubility

Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate, methanol. Insoluble in water.

Appearance

White or off-white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D5709 MSDS PDF

Info Sheet

D5709 Info Sheet PDF

References

Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-31. PMID: 16296875.

Eisenhauer EA, Vermorken JB. The taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs. 1998 Jan;55(1):5-30. PMID: 9463787.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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