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Doxazosin Mesylate

Doxazosin Mesylate

Product ID D5690
Cas No. 77883-43-3
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $93.60 In stock
250 mg $275.60 In stock
1 g $496.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Doxazosin is a quinazoline α1-adrenergic receptor inhibitor that exhibits antihypertensive and vasodilatory activities. Doxazosin is clinically used to treat hypertension and benign prostatic hyperplasia. Doxazosin induces Fas-mediated apoptosis in benign and malignant prostate cells.

Product Info

Cas No.

77883-43-3

Purity

≥98%

Formula

C23H25N5O5 • CH3SO3H

Formula Wt.

547.59

Chemical Name

1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3- dihydro-1,4-benzodioxan-2-yl)carbonyl)piperazine methanesulfonate

IUPAC Name

[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1, 4-benzodioxin-3-yl)methanone;methanesulfonic acid

Synonym

Doxazosin Methanesulfonate, Alfadil, Benur, Cardular, Carduran, Normothen, Supressin, Zoxan

Melting Point

275-277°C

Solubility

Slightly soluble in water.

Appearance

White or off-white Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D5690 MSDS PDF

Info Sheet

D5690 Info Sheet PDF

References

Shannon R, Chaudhry M. Effect of alpha1-adrenergic receptors in cardiac pathophysiology. Am Heart J. 2006 Nov;152(5):842-50. PMID: 17070143.

Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res. 2006 Jan 1;66(1):464-72. PMID: 16397262.

Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance. J Urol. 2003 Apr;169(4):1520-5. PMID: 12629407.

Custom Order

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