Echinacoside

Name: Echinacoside
SKU: E0929
Availability: InStock

Product ID E0929

Cas No. 82854-37-3

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Echinacoside is a phenylethanoid glycoside found in Echinacea, among other sources; it exhibits neuroprotective and vasodilatory activities. In vivo, echinacoside inhibits cytochrome c release and caspase-3 activation through modulation of ERK signaling, resulting in neuroprotection in a model of middle cerebral artery occlusion. Echinacoside also displays neuroprotective benefit in a MTPT-induced mouse model of Parkinson’s Disease, decreasing the Bax/Bcl-2 ratio and inhibiting suppression of dopamine and dopamine transporter (DAT) levels. This compound increases cGMP in rat aortic rings, inducing vasodilation. Additionally, echinacoside improves bone mineral density and microarchitecture, decreasing RANKL expression and increasing esteoprotegerin levels in animal models of osteopenia.

Product Info

Cas No.	82854-37-3
Purity	≥98%
Formula	C₃₅H₄₆O₂₀
Formula Wt.	786.73
Chemical Name	[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
IUPAC Name	[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R, 3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Solubility	Soluble in water and ethanol.
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	E0929 MSDS PDF
Info Sheet	E0929 Info Sheet PDF

References

Yang X, Li F, Yang Y, et al. Efficacy and safety of echinacoside in a rat osteopenia model. Evid Based Complement Alternat Med. 2013;2013:926928. PMID: 23573159.

Zhu M, Lu C, Li W. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80. PMID: 23189969.

Wei LL, Chen H, Jiang Y, et al. Effects of echinacoside on histio-central levels of active mass in middle cerebral artery occlusion rats. Biomed Environ Sci. 2012 Apr;25(2):238-44.PMID: 22998833.

Zhao Q, Gao J, Li W, et al. Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease. Brain Res. 2010 Jul 30;1346:224-36. PMID: 20478277.

He WJ, Fang TH, Ma X, et al. Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway. Planta Med. 2009 Oct;75(13):1400-4. PMID: 19468974.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Echinacoside

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Thienylheptyl Isothiocyanate

Manzamine A

NAP Peptide

Recombinant Multi-epitope Chimeric HCV Antigen

M2698

Transactivator of Transcription Peptide (2-4)

Monascorubrin

Mivacurium

5-Aminosalicylic Acid

Atorvastatin Calcium Trihydrate

Topotecan Hydrochloride

JWH 133

Cyproconazole

KT5720

LOXO-101

β-Cembrenediol Methyl Ether

Ferulic Acid Methyl Ester

Dimebon Dihydrochloride

N-Acetyl-S-(N-methylsulfinylbutylthiocarbamoyl)-L-cysteine

Brivudine

Footer