LKT Labs

Biochemicals for Life Science Research

Enalapril Maleate

Product ID E5201
Cas No. 76095-16-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $91.40 In stock
5 g $363.90 In stock
Bulk Quote

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Description

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits antihypertensive activity. Enalapril prevents and reverses renovascular hypertension-induced smooth muscle hypertrophy, collagen deposition, carotid media thickness growth, and other parameters of arterial remodeling. Additionally, enalapril improves endothelial function in migraine sufferers by increasing levels of NO.

Product Info

Cas No.

76095-16-4
Purity

≥98%
Formula

C20H28N2O5 • C4H4O4
Formula Wt.

492.52
Chemical Name

N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline maleate
IUPAC Name

(Z)-but-2-enedioic acid;(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino] propanoyl]pyrrolidine-2-carboxylic acid
Synonym

Amprace, Bitensil, Cardiovet, Enaloc, Innovace, Lotrial, Naprilene, Pres, Renivace, Xanef
Melting Point

143-144.5°C
Solubility

Sparingly soluble in water and methanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E5201 MSDS PDF
Info Sheet

E5201 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

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