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Ethacridine is an aromatic acridine derivative that exhibits antiseptic and abortifacient activities. Ethacridine intercalates DNA, increases levels of prostaglandin E (PGE), decreases excretion of estriol, and can induce fetal death in pregnant females.
| Cas No. | 6402-23-9 |
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| Purity | ≥98% |
| Formula | C15H15N3O • C3H6O3 • H2O |
| Formula Wt. | 361.39 |
| Chemical Name | 7-Ethoxy-3,9-acridinediamine lactate monohydrate |
| IUPAC Name | 7-ethoxyacridine-3,9-diamine;2-hydroxypropanoic acid;hydrate |
| Synonym | 2-ethoxy-6,9-diaminoacridine monolactate monohydrate, Acrino, Rimaon, Rivano, Vucine, Acrolactine, Ethodin, Metifex |
| Melting Point | 235°C |
| Solubility | Partially soluble in 15 parts water. Soluble in 9 parts boiling water. |
| Appearance | A Yellow Crystalline Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Mei Q, Li X, Liu H, et al. Effectiveness of mifepristone in combination with ethacridine lactate for second trimester pregnancy termination. Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:12-5. PMID: 24948048.
Oie S, Kamiya A. Microbial contamination of antiseptic-soaked cotton balls. Biol Pharm Bull. 1997 Jun;20(6):667-9. PMID: 9212987.
Tien KH. Intraamniotic injection of ethacridine for second-trimester induction of labor. Obstet Gynecol. 1983 Jun;61(6):733-6. PMID: 6843933.