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Ftorafur

Ftorafur

Product ID F7657
Cas No. 17902-23-7
Purity ≥99%
Product Unit SizeCostQuantityStock
250 mg $111.70 In stock
1 g $296.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ftorafur is an antimetabolite pyrimidine analog that exhibits anticancer chemotherapeutic activity. Ftorafur is a prodrug of 5-fluorouracil that inhibits thymidylate synthase, preventing thymidine synthesis. Ftorafur is typically clinically co-administered with other chemotherapeutics to decrease its peripheral cytotoxicity.

Product Info

Cas No.

17902-23-7

Purity

≥99%

Formula

C8H9FN2O3

Formula Wt.

200.17

Chemical Name

5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)- pyrimidinedione

IUPAC Name

5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione

Synonym

Tegafur, Citofur, Furafluor, 5-Fluoro-1-(tetrahydro-2-furyl)uracil

Melting Point

164-169°C

Solubility

Soluble in hot water, ethanol, methanol, or DMSO.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F7657 MSDS PDF

Info Sheet

F7657 Info Sheet PDF

References

Fukushima M. Antitumor activity and function of S-1, a new oral tegafur-based formulation. Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:19-26. PMID: 16897968.

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

Tanaka F, Fukuse T, Wada H, et al. The history, mechanism and clinical use of oral 5-fluorouracil derivative chemotherapeutic agents. Curr Pharm Biotechnol. 2000 Sep;1(2):137-64. PMID: 11467334.

Custom Order

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