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Fumonisin B1 is a mycotoxin initially produced by Fusarium that is found as a contaminant in grain, maize, and grapes. Fumonisin B1 inhibits sphingosine acyltransferase, disrupting sphingolipid metabolism. Fumonisin B1 is a less toxic analog of fumonisin B2.
| Cas No. | 116355-83-0 |
|---|---|
| Purity | ≥98% |
| Formula | C34H59NO15 |
| Formula Wt. | 721.83 |
| Chemical Name | 1,2,3-propanetricarboxylic acid 1,1'-[1-(12-amino- 4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methyl- pentyl)-1,2-ethanediyl] ester |
| IUPAC Name | (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3S)-3, 4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5, 9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
| Synonym | Macrofusine, FB1 |
| Melting Point | 126°C |
| Solubility | Soluble in PBS (18 mg/mL), methanol (10 mg/mL), and acetonitrile (10 mg/mL). |
| Appearance | Off White Powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Wei T, Zhu W, Pang M, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013 Dec;6(4):270-4. PMID: 24779936.
Tardieu D, Bailly JD, Skiba F, et al. Chronic toxicity of fumonisins in turkeys. Poult Sci. 2007 Sep;86(9):1887-93. PMID: 17704375.