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Geniposidic Acid

Geniposidic Acid

Product ID G1651
Cas No. 27741-01-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $107.30 In stock
5 mg $174.90 In stock
25 mg $525.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Geniposidic acid is an iridoid glucoside found in Eucommia, Castilleja, Plantago, and Gardenia species; it displays antihypertensive, anti-obesity, anti-inflammatory, antioxidative, and anticancer chemotherapeutic properties. In vivo, geniposidic acid promotes collagen synthesis and forms inter- and intra-molecular crosslinks within collagen fibers. Geniposidic acid also increases osteoblast proliferation and inhibits tumor growth in vivo. Additionally, this compound may also have benefit as a pesticide, as it is toxic to Kalotermes flavicollis termites and Crematogaster scutellaris ants.

Product Info

Cas No.

27741-01-1

Purity

≥98%

Formula

C16H22O10

Formula Wt.

374.34

Chemical Name

(1S,4aS,7aS)-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid

IUPAC Name

(1S,4aS,7aS)-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5, 7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid

Appearance

Off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G1651 MSDS PDF

Info Sheet

G1651 Info Sheet PDF

References

Hirata T, Kobayashi T, Wada A, et al. Anti-obesity compounds in green leaves of Eucommia ulmoides. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1786-91. PMID: 21324693.

Tzakou O, Mylonas P, Vagias C, et al. Iridoid glucosides with insecticidal activity from Galium melanantherum. Z Naturforsch C. 2007 Jul-Aug;62(7-8):597-602. PMID: 17913079.

Mi FL, Huang CT, Chiu YL, et al. Aglycone geniposidic acid, a naturally occurring crosslinking agent, and its application for the fixation of collagenous tissues. J Biomed Mater Res A. 2007 Dec 1;83(3):667-73. PMID: 17530623.

Ha H, Ho J, Shin S, et al. Effects of Eucommiae Cortex on osteoblast-like cell proliferation and osteoclast inhibition. Arch Pharm Res. 2003 Nov;26(11):929-36. PMID: 14661859.

Li Y, Sato T, Metori K, et al. The promoting effects of geniposidic acid and aucubin in Eucommia ulmoides Oliver leaves on collagen synthesis. Biol Pharm Bull. 1998 Dec;21(12):1306-10. PMID: 9881644.

Hsu HY, Yang JJ, Lin SY, et al. Comparisons of geniposidic acid and geniposide on antitumor and radioprotection after sublethal irradiation. Cancer Lett. 1997 Feb 26;113(1-2):31-7. PMID: 9065798.

Custom Order

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