LKT Labs

Biochemicals for Life Science Research

Ginsenoside F2

Ginsenoside F2

Product ID G3461
Cas No. 62025-49-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $115.00 In stock
5 mg $335.00 In stock
10 mg $475.00 In stock
Bulk Quote

Quicklinks

Description

Ginsenoside F2 is a triterpene saponin originally found in species of Panax that exhibits anti-obesity and anticancer chemotherapeutic activities. Ginsenoside F2 inhibits hair cell apoptosis, decreasing expression of TGF-β2, SCAP, and SREBP in vivo. Ginsenoside F2 also decreases lipid accumulation in adipocytes, suppressing expressing of PPARγ and perilipin and inhibiting adipogenesis. This compound also induces formation of acidic vesicles, autophagy, and mitochondrial apoptosis in breast cancer stem cells; additionally, it decreases tumor growth in animal models of glioblastoma.

Product Info

Cas No.

62025-49-4
Purity

≥98%
Formula

C42H72O13
Formula Wt.

785.03
IUPAC Name

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

G3461 MSDS PDF
Info Sheet

G3461 Info Sheet PDF

References

Shin HS, Park SY, Hwang ES, et al. Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. Biol Pharm Bull. 2014;37(5):755-63. PMID: 24789999.

Siraj FM, Sathishkumar N, Kim YJ, et al. Ginsenoside F2 possesses anti-obesity activity via binding with PPARγ and inhibiting adipocyte differentiation in the 3T3-L1 cell line. J Enzyme Inhib Med Chem. 2014 Mar 25. [Epub ahead of print]. PMID: 24666293.

Mai TT, Moon J, Song Y, et al. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett. 2012 Aug 28;321(2):144-53. PMID: 22326284.

Quan LH, Piao JY, Min JW, et al. Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102. J Ginseng Res. 2011 Sep;35(3):344-51. PMID: 23717079.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G3352

    Ginkgolic Acid (13:0)

    Alkylphenol found in Ginkgo; HIV protease inhib...

    ≥98%
  • Z0944

    ZCL-278

    Cdc42 inhibitor.

    ≥98%
  • C5600

    CO-1686

    EGFR (WT, T790M) inhibitor.

    ≥98%
  • M1644

    Meloxicam

    NSAID; COX-2 inhibitor.

    ≥98%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • T7133

    Trimetazidine Dihydrochloride

    Long-chain 3-ketoacyl-CoA thiolase inhibitor, p...

    ≥99%
  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • C1718

    Cepharanthine, 95%

    Alkaloid found in Stephania.

    ≥95%
  • T162051

    Tebipenem

    Broad-spectrum antibiotic

    ≥99%
  • I5315

    Indomethacin

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • C4756

    Cloxacillin Sodium Monohydrate

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • M3196

    MHY-1485

    mTOR activator.

    ≥98%
  • A145823

    ADU-S100 sodium salt

    Synthetic cyclic dinucleotide agonist of STING....

    ≥99%
  • P7057

    Protodioscin

    Saponin found in Dioscorea; Na+/K+ ATPase and C...

    ≥98%
  • M7528

    α-Melanocyte Stimulating Hormone

    Endogenous peptide hormone derived from POMC, i...

    ≥98%
  • S9755

    (R)-Synephrine

    Synephrine is an endogenous alkaloid.

    ≥98%
  • V3476

    Vitamin D2

    Vitamin D prodrug produced by fungi and alfalfa...

    ≥91%
  • L1782

    Levodopa

    Endogenous catecholamine precursor, also found ...

    ≥98%
  • P7023

    Pregnenolone

    Endogenous precursor to all steroid hormones; T...

    ≥98%
  • A0910

    N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%