• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Gonadorelin Acetate

Gonadorelin Acetate

Product ID G5752
Cas No. 71447-49-9
Purity ≥95%
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Gonadorelin is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH) or luteinizing hormone releasing hormone (LHRH). Gonadorelin acts as an agonist at the GnRH/LHRH receptor, inducing release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This hormone is clinically used to treat endometriosis. Gonadorelin exhibits anti-androgen and anticancer chemotherapeutic activities. In vitro and in vivo, gonadorelin inhibits testosterone activation of androgen receptors. Additionally, gonadorelin increases proliferation of normal cells but inhibits proliferation of prostate cancer cells through a mechanism that involved activation of the ryanodine receptor and increases in intracellular Ca2+ levels.

Product Info

Cas No.

71447-49-9

Purity

≥95%

Formula

C55H75N17O13 • 2(C2H4O2)

Formula Wt.

1302.59

IUPAC Name

acetic acid;N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide;hydrate

Synonym

Luteinizing hormone-releasing factor acetate, LH-RH

Solubility

Soluble in water, methanol.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G5752 MSDS PDF

Info Sheet

G5752 Info Sheet PDF

References

Maudsley S, Davidson L, Pawson AJ, et al. Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5. Neuroendocrinology. 2006;84(5):285-300. PMID: 17202804.

Maiti K, Oh DY, Moon JS, et al. Differential effects of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on prostate cancer cell signaling and death. J Clin Endocrinol Metab. 2005 Jul;90(7):4287-98. PMID: 15870130.

Enomoto M, Park MK. GnRH as a cell proliferation regulator: mechanism of action and evolutionary implications. Zoolog Sci. 2004 Oct;21(10):1005-13. PMID: 15514469.

Shalev E, Leung PC. Gonadotropin-releasing hormone and reproductive medicine. J Obstet Gynaecol Can. 2003 Feb;25(2):98-113. PMID: 12577127.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E6235

    Epirubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥90%
  • A7460

    Asparaginase

    Catalyzes hydrolysis of asparagine.

    ≥98%
  • A0534

    Abiraterone

    Progesterone derivative; Cyp17A1 inhibitor.

    ≥99%
  • R0243

    Raloxifene Hydrochloride

    SERM.

    ≥98%
  • C8070

    Curcumin, high purity

    Active compound found in turmeric; MST1 activat...

    ≥98%
  • G3252

    6-Gingerol

    Phenol found in Zingiber; TRPV1 agonist, 5-HT3 ...

    ≥98%
  • A528251

    Angiotensin I/II (1-7)(DP-7)

    Peptide fragment

    ≥95%
  • C3479

    Citrinin

    Mycotoxin produced by Penicillum, Aspergillus, ...

    ≥98%
  • M7200

    MS436

    BRD4 inhibitor.

    ≥99%
  • A4534

    Aliskiren Hemifumarate

    Renin inhibitor.

    ≥98%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • C002041

    Cabazitaxel

    Taxoid that disrupts the microtubular network i...

    ≥98%
  • A4853

    β-Amyloid Peptide (1-42), human

    Endogenous APP peptide cleavage product, primar...

    ≥95%
  • V2792

    VGX-1027

    TLR4 inhibitor.

    ≥98%
  • N0114

    Nadifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • O6932

    Oridonin

    Diterpenoid found in Rabdosia rubescens; potent...

    ≥98%
  • C084099

    CCCP

    Efflux pump inhibitor

    ≥99%
  • K2412

    KGDS

    Synthetic peptide, fibrinogen derivative; glyco...

    ≥95%
  • E9418

    Exendin 3 (9-39)

    Peptide, GLP-1 analog found in Heloderma; GLP-1...

    ≥95%
  • A7400

    ASP3026

    ALK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only