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Growth hormone-releasing factor is an endogenous peptide hormone that enhances follicle-stimulating hormone (FSH)-induced steroidogenesis in vitro and inhibits myosin light chain kinase (MLCK) activity. Additionally, this peptide increases locomotor activity, preventing habituation.
| Cas No. | 83930-13-6 |
|---|---|
| Purity | ≥98% |
| Formula | C215H358N72O66S |
| Formula Wt. | 5039.70 |
| Synonym | Growth Hormone Releasing Hormone, GRF, GHRF, GHRH, GRF (1-44), amide, human. |
| Solubility | Soluble in water, acetic acid, TFA. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Karakji EG, Tsang BK. Growth hormone releasing factor and vasoactive intestinal peptide stimulate rat granulosa cell plasminogen activator activity in vitro during follicular development. Mol Cell Endocrinol. 1995 Jan;107(1):105-12. PMID: 7796929.
Shiraga H, Stallwood D, Ebadi M, et al. Inhibition of calmodulin-dependent myosin light-chain kinase by growth-hormone-releasing factor and vasoactive intestinal peptide. Biochem J. 1994 Jun 15;300 ( Pt 3):901-5. PMID: 8010976.
Alvarez XA, Cacabelos R. Influence of growth hormone (GH) and GH-releasing factor on locomotor activity in rats. Peptides. 1993 Jul-Aug;14(4):707-12. PMID: 8234013.
